4.4 Article

A Novel Shiga Toxin 1a-Converting Bacteriophage of Shigella sonnei With Close Relationship to Shiga Toxin 2-Converting Pages of Escherichia coli

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OPEN FORUM INFECTIOUS DISEASES
卷 3, 期 2, 页码 -

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OXFORD UNIV PRESS INC
DOI: 10.1093/ofid/ofw079

关键词

bacteriophages; Shigella sonnei; Shiga toxin

资金

  1. National Institutes of Health [AI093163]

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In recent studies, strains of non-dysenteriae 1 Shigella (NDS) expressing Shiga toxin have been reported. In this study, we report a novel stx1a-converting bacteriophage of Shigella sonnei associated with travel to Mexico. Phylogenetic comparison between this and other stx-converting phages suggests that toxigenic NDS strains have arisen through separate horizontal transfer events from toxigenic Escherichia coli.

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