期刊
AGING CLINICAL AND EXPERIMENTAL RESEARCH
卷 34, 期 3, 页码 687-690出版社
SPRINGER
DOI: 10.1007/s40520-021-01993-x
关键词
Centenarians; Biological frailty index; Biological reserves; Longevity
资金
- Italian Ministry of University and Research (PRIN 2006)
- Italian Ministry of University and Research (PRIN 2009)
The study measured the subclinical frailty of centenarians by calculating a Biological Frailty Index (FI), showing that centenarians have narrower distribution of biological reserves without significant gender differences. The findings suggest that the exceptional biological reserves of centenarians may be underestimated in clinical assessments.
This study measured the subclinical frailty of centenarians by looking at the accumulation of their biological abnormalities. For this aim, a biological Frailty Index (FI) was computed in centenarians living in Northern Italy. The median value of the biological FI was 0.33 (interquartile range, IQR 0.28-0.41). The biological FI did not significantly differ between women (0.34, IQR 0.31-0.39) and men (0.32, IQR 0.26-0.43). The biological FI seems to have a narrower distribution compared to clinical FI we previously computed in the same cohort. In conclusion, our study suggests that centenarians benefit from exceptional biological reserves that might be underestimated by clinical appearances.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据