4.3 Article

Excess branched-chain amino acids alter myotube metabolism and substrate preference which is worsened by concurrent insulin resistance

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Agriculture, Dairy & Animal Science

MiR-19 3b regulated the formation of coat colors by targeting WNT10A and GNAI2 in Cashmere goats

Ba Xiang et al.

Summary: MiRNAs are a group of small noncoding RNAs that play a crucial role in regulating coat color and hair follicle development. This study found that miR-193b may be involved in regulating coat color in Cashmere goat skin tissue by targeting WNT10A and GNAI2.

ANIMAL BIOTECHNOLOGY (2023)

Article Endocrinology & Metabolism

Branched-chain amino acids at supraphysiological but not physiological levels reduce myotube insulin sensitivity

Madison E. Rivera et al.

Summary: The study aimed to examine the effect of a BCAA mixture on muscle insulin signaling in vitro, showing that BCAA treatment could reduce basal insulin signaling in healthy cells and insulin-stimulated insulin signaling in insulin resistant cells. However, further investigation is needed to determine the extent of these observations in vivo models.

DIABETES-METABOLISM RESEARCH AND REVIEWS (2022)

Review Endocrinology & Metabolism

Essential amino acid formulations to prevent mitochondrial dysfunction and oxidative stress

Chiara Ruocco et al.

Summary: Restriction and supplementation of specific amino acids or BCAAs can improve metabolic homeostasis, energy balance, and health span. Recent research shows that a mixture of EAAs and BCAAs can extend healthy lifespan by promoting mitochondrial biogenesis and activating antioxidant defense systems. New formulas enriched with Krebs cycle substrates may be more efficient than BCAA-enriched mixtures in improving mitochondrial health and overall well-being.

CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE (2021)

Article Biochemistry & Molecular Biology

Effect of the protein hydrolysate of rice syrup meal on the endurance exercise performance of BALB/c mice

Yeok Boo Chang et al.

Summary: This study investigated the muscular endurance and anti-fatigue effects of the protein hydrolysate of rice syrup meal in mouse models. The results showed that the protein hydrolysate significantly improved endurance performance and reduced fatigue by enhancing energy metabolism and decreasing reactive oxygen species accumulation. It can be considered as an effective natural resource for enhancing muscular endurance and combating fatigue.

FOOD & FUNCTION (2021)

Article Endocrinology & Metabolism

Leucine decreases intramyocellular lipid deposition in an mTORC1-independent manner in palmitate-treated C2C12 myotubes

Hexirui Wu et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2020)

Article Cell Biology

Effect of valine on myotube insulin sensitivity and metabolism with and without insulin resistance

Madison E. Rivera et al.

MOLECULAR AND CELLULAR BIOCHEMISTRY (2020)

Article Cell Biology

Exploring mechanistic links between extracellular branched-chain amino acids and muscle insulin resistance: an in vitro approach

Hannah Crossland et al.

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2020)

Review Environmental Sciences

PGC-1α-Targeted Therapeutic Approaches to Enhance Muscle Recovery in Aging

Jonathan J. Petrocelli et al.

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2020)

Article Gastroenterology & Hepatology

A specific amino acid formula prevents alcoholic liver disease in rodents

Laura Tedesco et al.

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2018)

Review Food Science & Technology

BCAA Metabolism and Insulin Sensitivity - Dysregulated by Metabolic Status?

Nicholas P. Gannon et al.

MOLECULAR NUTRITION & FOOD RESEARCH (2018)

Review Endocrinology & Metabolism

Branched Chain Amino Acids in Metabolic Disease

Zoltan Arany et al.

CURRENT DIABETES REPORTS (2018)

Review Biochemistry & Molecular Biology

Leucine-induced anabolic-catabolism: two sides of the same coin

Nicholas P. Gannon et al.

AMINO ACIDS (2016)

Review Endocrinology & Metabolism

Branched-chain amino acids in metabolic signalling and insulin resistance

Christopher J. Lynch et al.

NATURE REVIEWS ENDOCRINOLOGY (2014)

Article Nutrition & Dietetics

Leucine Modulates Mitochondrial Biogenesis and SIRT1-AMPK Signaling in C2C12 Myotubes

Chunzi Liang et al.

JOURNAL OF NUTRITION AND METABOLISM (2014)

Article Nutrition & Dietetics

Co-ingestion of carbohydrate and whey protein isolates enhance PGC-1α mRNA expression: a randomised, single blind, cross over study

Karen M. Hill et al.

JOURNAL OF THE INTERNATIONAL SOCIETY OF SPORTS NUTRITION (2013)

Review Cell Biology

Dual control of mitochondrial biogenesis by sirtuin 1 and sirtuin 3

Julia Brenmoehl et al.

MITOCHONDRION (2013)

Article Nutrition & Dietetics

Determination of the tolerable upper intake level of leucine in acute dietary studies in young men

Rajavel Elango et al.

AMERICAN JOURNAL OF CLINICAL NUTRITION (2012)

Article Endocrinology & Metabolism

Leucine supplementation increases SIRT1 expression and prevents mitochondrial dysfunction and metabolic disorders in high-fat diet-induced obese mice

Hongliang Li et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2012)

Review Biochemistry & Molecular Biology

Metabolic control of mitochondrial biogenesis through the PGC-1 family regulatory network

Richard C. Scarpulla

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2011)

Article Cardiac & Cardiovascular Systems

Morphometric changes induced by amino acid supplementation in skeletal and cardiac muscles of old mice

Giovanni Corsetti et al.

AMERICAN JOURNAL OF CARDIOLOGY (2008)

Article Multidisciplinary Sciences

AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1α

Sibylle Jaeger et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Multidisciplinary Sciences

Resveratrol improves health and survival of mice on a high-calorie diet

Joseph A. Baur et al.

NATURE (2006)

Article Pharmacology & Pharmacy

Development of insulin resistance and reversal by thiazolidinediones in C2C12 skeletal muscle cells

N Kumar et al.

BIOCHEMICAL PHARMACOLOGY (2003)

Article Multidisciplinary Sciences

AMP kinase is required for mitochondrial biogenesis in skeletal muscle in response to chronic energy deprivation

HH Zong et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)