Putting the Squeeze on Phase Separation

Phase separation is a ubiquitous process and finds applications in a variety of biological, organic, and inorganic systems. Nature has evolved the ability to control phase separation to both regulate cellular processes and make composite materials with outstanding mechanical and optical properties. Striking examples of the latter are the vibrant blue and green feathers of many bird species, which are thought to result from an exquisite control of the size and spatial correlations of their phase-separated microstructures. By contrast, it is much harder for material scientists to arrest and control phase separation in synthetic materials with such a high level of precision at these length scales. In this Perspective, we briefly review some established methods to control liquid-liquid phase separation processes and then highlight the emergence of a promising arrest method based on phase separation in an elastic polymer network. Finally, we discuss upcoming challenges and opportunities for fabricating microstructured materials via mechanically controlled phase separation.

Automated summary

Phase separation is a common process in various biological, organic, and inorganic systems, playing a role in regulating cellular processes and creating composite materials. While nature demonstrates precise control over phase separation for vibrant colors in bird feathers, achieving the same level of precision in synthetic materials presents challenges. Emerging methods based on elastic polymer networks show promise in controlling phase separation.