Emerging Applications of Aryl Trifluoromethyl Diazoalkanes and Diazirines in Synthetic Transformations

Aryl trifluoromethyl diazoalkanes and diazirines have become unique as reactants in synthetic methodology. As privileged compounds containing CF3 groups and ease of synthetic access, aryl trifluoromethyl diazoalkanes and diazirines have been highlighted for their versatility in applications toward a wide range of synthetic transformations. This Perspective highlights the synthetic applications of these reactants as precursors of stabilized metal carbenes, i.e., donor-acceptor-substituted ones.

Automated summary

Aryl trifluoromethyl diazoalkanes and diazirines have become unique reactants in synthetic methodology. Highlighted for their versatility in applications towards a wide range of synthetic transformations, these compounds, bearing CF3 groups and accessible for synthesis, are valuable as precursors of stabilized metal carbenes.