期刊
CURRENT ADDICTION REPORTS
卷 9, 期 1, 页码 23-31出版社
SPRINGERNATURE
DOI: 10.1007/s40429-021-00403-6
关键词
Compulsive sexual behavior disorder; Hypersexuality; Sexual addiction; HPG axis; HPA axis; Oxytocin
资金
- Umea University
Evidence suggests that the neuroendocrine and hormonal systems are involved in the pathophysiology of compulsive sexual behavior disorder. The hypothalamus-pituitary adrenal axis, the hypothalamus-pituitary-gonadal axis, and the oxytocinergic system have been implicated.
Purpose of Review Compulsive sexual behavior disorder has been recently included in the 11th revision of the International Classification of Diseases (ICD-11), and the possible contribution of neurochemical and hormonal factors have been reported. However, relatively little is known concerning the neurobiology underlying this disorder. The aim of this article is to review and discuss published findings in the area. Recent Findings Evidence suggests that the neuroendocrine systems are involved in the pathophysiology of compulsive sexual behavior. The hypothalamus-pituitary adrenal axis, the hypothalamus-pituitary-gonadal axis, and the oxytocinergic system have been implicated. Summary Further studies are needed to elucidate the exact involvement of neuroendocrine and hormonal systems in compulsive sexual behavior disorder. Prospective longitudinal studies are particularly needed, especially those considering co-occurring psychiatric disorders and obtaining hormonal assessments in experimental circumstances with appropriate control groups.
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