4.6 Review

Military traumatic brain injury: a challenge straddling neurology and psychiatry

期刊

MILITARY MEDICAL RESEARCH
卷 9, 期 1, 页码 -

出版社

BMC
DOI: 10.1186/s40779-021-00363-y

关键词

Shellshock; Military; Traumatic brain injury; Diagnosis; Treatment; Comorbidity

资金

  1. Zhejiang Provincial Key Research and Development Program [2021C03107]

向作者/读者索取更多资源

Military psychiatry, a new subcategory of psychiatry, is playing an important role in war. This review examines military research, summarizes epidemiological data, neuropathology, and research achievements in diagnosis and treatment technology, and discusses the comorbidity and sequelae of military traumatic brain injury (TBI). Advances in neuroimaging and molecular biology have greatly enhanced the understanding of TBI, revealing abnormal protein accumulation and brain metabolism abnormalities involved in its development. TBI, based on organic injury, is distinct from other mental disorders and presents a new challenge at the intersection of neurology and psychiatry.
Military psychiatry, a new subcategory of psychiatry, has become an invaluable, intangible effect of the war. In this review, we begin by examining related military research, summarizing the related epidemiological data, neuropathology, and the research achievements of diagnosis and treatment technology, and discussing its comorbidity and sequelae. To date, advances in neuroimaging and molecular biology have greatly boosted the studies on military traumatic brain injury (TBI). In particular, in terms of pathophysiological mechanisms, several preclinical studies have identified abnormal protein accumulation, blood-brain barrier damage, and brain metabolism abnormalities involved in the development of TBI. As an important concept in the field of psychiatry, TBI is based on organic injury, which is largely different from many other mental disorders. Therefore, military TBI is both neuropathic and psychopathic, and is an emerging challenge at the intersection of neurology and psychiatry.

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