期刊
ACS OMEGA
卷 7, 期 1, 页码 1329-1336出版社
AMER CHEMICAL SOC
DOI: 10.1021/acsomega.1c05955
关键词
-
资金
- Academy of Finland [308931, 318890, 318891, 337430]
- Academy of Finland (AKA) [308931, 337430, 308931] Funding Source: Academy of Finland (AKA)
The Bingel cyclopropanation reaction was used to produce a hexakis-functionalized C-60 core, which can be selectively functionalized by two pericyclic click reactions, allowing control over the assembly of heteroantennary bioconjugates with appropriate ligands.
Bingel cyclopropanation between Buckminster fullerene and a heteroarmed malonate was utilized to produce a hexakis-functionalized C-60 core, with azide and tetrazine units. This orthogonally bifunctional C-60 scaffold can be selectively one-pot functionalized by two pericyclic click reactions, that is, inverse electron-demand Diels-Alder and azide-alkyne cycloaddition, which with appropriate ligands (monosaccharides, a peptide and oligonucleotides tested) allows one to control the assembly of heteroantennary bioconjugates.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据