Double Balloon Enteroscopy in a Pregnant Woman with Peutz-Jeghers Syndrome

Peutz-Jeghers syndrome is an autosomal dominant disorder characterised by multiple hamartomatous polyps and muco-cutaneous pigmentation. Most polyps are found in the small intestine, especially in the jejunum. Enteroscopy with polypectomy is a reliable method to prevent polyp-related complications. A pregnant woman, who was diagnosed as a case of Peutz-Jeghers syndrome with a history of intestinal resection, was admitted to our clinic. Termination was recommended to the patient due to the possibility of polyps, causing obstruction during pregnancy. She underwent double balloon enteroscopy in the second trimester. Large polyps that could cause intussusception were removed and post-polypectomy bleeding was successfully controlled. This procedure was the first double balloon enteroscopy during pregnancy, reported in the literature. The procedure should be performed by experienced endoscopists, who can cope well with the complications in expert centres, as the procedure carries a high risk.

Automated summary

Peutz-Jeghers syndrome is an autosomal dominant disorder characterized by multiple hamartomatous polyps in the small intestine. This case report describes the first double balloon enteroscopy during pregnancy for a patient with a history of intestinal resection due to the syndrome. Experienced endoscopists in expert centers should perform the procedure to manage the high-risk complications effectively.