4.4 Review

Three-dimensional printed dosage forms based on disease-focussed perspectives

期刊

JOURNAL OF PHARMACY AND PHARMACOLOGY
卷 74, 期 10, 页码 1406-1426

出版社

OXFORD UNIV PRESS
DOI: 10.1093/jpp/rgab139

关键词

3D printing; personalized medicine; disease focussed; 3D printed dosage forms; drug delivery

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This review provides an overview of the use of 3DP technologies in the pharmaceutical field, including their working principles and critical process parameters. It also presents a novel approach to evaluate the application of 3DP technologies in the treatment of different diseases.
Objectives Three-dimensional printing (3DP) has gained importance worldwide recently as a novel drug manufacturing technology. 3DP technologies are suitable in the pharmaceutical field because of having the potential in personalized medicine. The aim of this review is to present an overview of the use of 3DP technologies in pharmaceutical area, their working principles and critical process parameters. In addition, this review presents an innovative approach that evaluates the use of 3DP technologies on disease to disease. Key findings This review covers the potential use of 3DP technologies in different diseases by evaluating them on a research basis. These diseases can be summarized as cardiovascular, neurological, respiratory, oncological, inflammatory, vaginal, dermatological and other diseases. It has been focussed on manuscripts that published after 2015. Studies on the use of 3DP in each disease group have been systematically reviewed by considering the methods, types of printers used and the prepared dosage forms. Oral formulations (tablets and films), implants, topical systems and vaccines are some of the examples of the mentioned dosage forms. This review presented a systematic and novel overview of the use of 3DP in the treatment of different clinical disorders.

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