期刊
PATHOLOGY & ONCOLOGY RESEARCH
卷 28, 期 -, 页码 -出版社
FRONTIERS MEDIA SA
DOI: 10.3389/pore.2022.1610133
关键词
traditional serrated adenoma; gallbladder; dysplasia; serrated-pathway; TSA
While the majority of laparoscopic cholecystectomy specimens show typical findings, sometimes unusual structures can be found. In our case, a 67-year-old woman underwent routine laparoscopic cholecystectomy and was diagnosed with a rare traditional serrated adenoma of the gallbladder.
While overwhelming majority of laparoscopic cholecystectomy specimens performed for gallstones or cholecystitis show rather typical findings, sometimes polypoid structures are also removed. These can be related to cholesterolosis or conventional adenomas, but occasionally extraordinary findings do emerge. In our case, a 67-year old lady with typical complaints of cholecystitis underwent routine laparoscopic cholecystectomy. Preoperative ultrasound revealed a polypoid mass with inflammation and without suspicion for malignancy. Microscopic examination showed partly conventional, low-grade dysplastic crypts forming a villous and rather complex structure. Ectopic crypt foci, slit-like serration pattern and serrated dysplasia with eosinophylic cytoplasm and centrally located nuclei were seen throughout the lesion, thus a traditional serrated adenoma (TSA) of the gallbladder was diagnosed. TSA represents the rarest subtype of serrated lesions in the colon and extracolonic manifestations are sporadically reported. Until now only a single case of a serrated adenoma was reported from the gallbladder. Here we describe the detailed clinical, pathological and molecular findings of our case and discuss these in the light of current literature data regarding this field.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据