期刊
ORGANIC & BIOMOLECULAR CHEMISTRY
卷 20, 期 12, 页码 2392-2396出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/d2ob00177b
关键词
-
The dynamic kinetic resolution of C-N atropisomeric pyridones was achieved via asymmetric phase-transfer catalysis, utilizing a hydrogen bond and pi interaction. The study revealed key non-covalent interactions between the substrate and catalyst.
The dynamic kinetic resolution of C-N atropisomeric pyridones was achieved via asymmetric phase-transfer catalysis, exploiting a rotational barrier-lowering hydrogen bond in the starting materials. X-ray and NMR experiments revealed the presence of a barrier-raising ground state CHMIDLINE HORIZONTAL ELLIPSIS pi interaction in the product, supported by DFT calculations. A co-crystal of the quinidine-derived phase-transfer catalyst and substrate reveals key substrate-catalyst non-covalent interactions.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据