相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Estrogen Signaling Induces Mitochondrial Dysfunction-Associated Autophagy and Senescence in Breast Cancer Cells
Khuloud Bajbouj et al.
BIOLOGY-BASEL (2020)
Lactate Activates the E2F Pathway to Promote Cell Motility by Up-Regulating Microtubule Modulating Genes
Yi-deun Jung et al.
CANCERS (2019)
Metformin in patients with and without diabetes: a paradigm shift in cardiovascular disease management
Fei Luo et al.
CARDIOVASCULAR DIABETOLOGY (2019)
Metformin attenuates hypoxia-induced resistance to cisplatin in the HepG2 cell line
Hiromasa Fujita et al.
ONCOLOGY LETTERS (2019)
Metformin Induces Apoptosis and Inhibits Proliferation through the AMP-Activated Protein Kinase and Insulin-like Growth Factor 1 Receptor Pathways in the Bile Duct Cancer Cells
Jin Lee et al.
JOURNAL OF CANCER (2019)
Actions of metformin and statins on lipid and glucose metabolism and possible benefit of combination therapy
Mariel F. van Stee et al.
CARDIOVASCULAR DIABETOLOGY (2018)
Metformin Induces Apoptosis and Alters Cellular Responses to Oxidative Stress in Ht29 Colon Cancer Cells: Preliminary Findings
Paola Sena et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Effect of metformin monotherapy on serum lipid profile in statin-naive individuals with newly diagnosed type 2 diabetes mellitus: a cohort study
Szu Han Lin et al.
PEERJ (2018)
Naringin Activates AMPK Resulting in Altered Expression of SREBPs, PCSK9, and LDLR To Reduce Body Weight in Obese C57BL/6J Mice
Guo-Guang Sui et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2018)
Hepatic HNF1 transcription factors control the induction of PCSK9 mediated by rosuvastatin in normolipidemic hamsters
Bin Dong et al.
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2017)
Hypoxia reduces HNF4α/MODY1 protein expression in pancreatic β-cells by activating AMP-activated protein kinase
Yoshifumi Sato et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
In vitro cellular models of human hepatic fatty acid metabolism: differences between Huh7 and HepG2 cell lines in human and fetal bovine culturing serum
Pippa J. Gunn et al.
PHYSIOLOGICAL REPORTS (2017)
The mechanisms of action of metformin
Graham Rena et al.
DIABETOLOGIA (2017)
Metformin prevents ischaemic ventricular fibrillation in metabolically normal pigs
Li Lu et al.
DIABETOLOGIA (2017)
Therapeutic Concentrations of Metformin: A Systematic Review
Farshad Kajbaf et al.
CLINICAL PHARMACOKINETICS (2016)
Effects of Metformin on Metabolite Profiles and LDL Cholesterol in Patients With Type 2 Diabetes
Tao Xu et al.
DIABETES CARE (2015)
Novel therapeutic targets of metformin: metabolic syndrome and cardiovascular disease
Ricardo Ladeiras-Lopes et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2015)
Reduction of circulating PCSK9 and LDL-C levels by liver-specific knockdown of HNF1α in normolipidemic mice
Vikram Ravindra Shende et al.
JOURNAL OF LIPID RESEARCH (2015)
Metformin inhibits hepatocellular glucose, lipid and cholesterol biosynthetic pathways by transcriptionally suppressing steroid receptor coactivator 2 (SRC-2)
Andre Madsen et al.
SCIENTIFIC REPORTS (2015)
Metformin protects primary rat hepatocytes against oxidative stress-induced apoptosis
Laura Conde de la Rosa et al.
PHARMACOLOGY RESEARCH & PERSPECTIVES (2015)
Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism
Joao Fadista et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Effects of Metformin Versus Glipizide on Cardiovascular Outcomes in Patients With Type 2 Diabetes and Coronary Artery Disease
Jie Hong et al.
DIABETES CARE (2013)
Metformin Protects Rat Hepatocytes against Bile Acid-Induced Apoptosis
Titia E. Woudenberg-Vrenken et al.
PLOS ONE (2013)
Cellular and molecular mechanisms of metformin: an overview
Benoit Viollet et al.
CLINICAL SCIENCE (2012)
Metformin-Induced Hepatotoxicity
Francisco Miralles-Linares et al.
DIABETES CARE (2012)
Cross-regulation of hepatic glucose metabolism via ChREBP and nuclear receptors
Audrey Poupeau et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2011)
AMPK Phosphorylates and Inhibits SREBP Activity to Attenuate Hepatic Steatosis and Atherosclerosis in Diet-Induced Insulin-Resistant Mice
Yu Li et al.
CELL METABOLISM (2011)
Hepatotoxicity Associated with Metformin Therapy in Treatment of Type 2 Diabetes Mellitus with Nonalcoholic Fatty Liver Disease
Catherine J. Cone et al.
ANNALS OF PHARMACOTHERAPY (2010)
Metformin regulates palmitate-induced apoptosis and ER stress response in HepG2 liver cells
Do-Sung Kim et al.
IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY (2010)
被撤回的出版物: AMP-activated Protein Kinase Mediates Apoptosis in Response to Bioenergetic Stress through Activation of the Pro-apoptotic Bcl-2 Homology Domain-3-only Protein BMF (Retracted article. See vol. 295, pg. 671, 2020)
Sean M. Kilbride et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Strong induction of PCSK9 gene expression through HNF1α and SREBP2: mechanism for the resistance to LDL-cholesterol lowering effect of statins in dyslipidemic hamsters
Bin Dong et al.
JOURNAL OF LIPID RESEARCH (2010)
Clarifying metformin's role and risks in liver dysfunction
Carolyn C. Brackett
JOURNAL OF THE AMERICAN PHARMACISTS ASSOCIATION (2010)
Treatment of Insulin Resistance with Metformin in Naive Genotype 1 Chronic Hepatitis C Patients Receiving Peginterferon Alfa-2a Plus Ribavirin
Manuel Romero-Gomez et al.
HEPATOLOGY (2009)
Antagonism of Secreted PCSK9 Increases Low Density Lipoprotein Receptor Expression in HepG2 Cells
Markey C. McNutt et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Hnf1α (MODY3) Controls Tissue-Specific Transcriptional Programs and Exerts Opposed Effects on Cell Growth in Pancreatic Islets and Liver
Joan-Marc Servitja et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
Meta-analysis: Metformin treatment in persons at risk for diabetes mellitus
Shelley R. Salpeter et al.
AMERICAN JOURNAL OF MEDICINE (2008)
Metformin and the intestine
C. J. Bailey et al.
DIABETOLOGIA (2008)
Plasma PCSK9 preferentially reduces liver LDL receptors in mice
Aldo Grefhorst et al.
JOURNAL OF LIPID RESEARCH (2008)
Plasma PCSK9 levels are significantly modified by statins and fibrates in humans
Janice Mayne et al.
LIPIDS IN HEALTH AND DISEASE (2008)
Sterol-dependent regulation of proprotein convertase subtilisin/kexin type 9 expression by sterol-regulatory element binding protein-2
Hyun Jeong Jeong et al.
JOURNAL OF LIPID RESEARCH (2008)
Binding of proprotein convertase subtilisin/kexin type 9 to epidermal growth factor-like repeat a of low density lipoprotein receptor decreases receptor recycling and increases degradation
Da-Wei Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Activation of AMP-activated protein kinase in the liver: a new strategy for the management of metabolic hepatic disorders
Benoit Viollet et al.
JOURNAL OF PHYSIOLOGY-LONDON (2006)
Hepatic PCSK9 expression is regulated by nutritional status via insulin and sterol regulatory element-binding protein 1c
P Costet et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
The effect of metformin on blood pressure, plasma cholesterol and triglycerides in type 2 diabetes mellitus:: a systematic review
MG Wulffelé et al.
JOURNAL OF INTERNAL MEDICINE (2004)
Mutations in PCSK9 cause autosomal dominant hypercholesterolemia
M Abifadel et al.
NATURE GENETICS (2003)
The antidiabetic drug metformin activates the AMP-activated protein kinase cascade via an adenine nucleotide-independent mechanism
SA Hawley et al.
DIABETES (2002)
Hepatocyte nuclear factor-4α involved in type 1 maturity-onset diabetes of the young is a novel target of AMP-activated protein kinase
I Leclerc et al.
DIABETES (2001)
分享论文
