4.3 Article

Spinal epidural lipomatosis: a rare and frequently unrecognized complication of Cushing syndrome

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Spinal Epidural Lipomatosis: A Comprehensive Review

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Summary: Spinal epidural lipomatosis (SEL) is a rare condition characterized by excessive accumulation of adipose tissue in the thoracic and lumbar regions of the spine. While the exact pathogenesis is not fully understood, common risk factors include exogenous steroid use, obesity, endogenous steroid hormonal disease, spine surgery, and idiopathic disease. Progression of SEL can lead to neurological deficits and various symptoms related to spinal cord compression, with treatment options ranging from conservative management to minimally invasive and open surgical techniques.

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