4.8 Article

The role of the atypical chemokine receptor CCRL2 in myelodysplastic syndrome and secondary acute myeloid leukemia

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Oncology

Fedratinib, a newly approved treatment for patients with myeloproliferative neoplasm-associated myelofibrosis

Moshe Talpaz et al.

Summary: Myelofibrosis is a serious bone marrow disorder characterized by splenomegaly, and Fedratinib, a selective JAK2 inhibitor, has shown promising results in treating MF patients by targeting the JAK/STAT signaling pathway.

LEUKEMIA (2021)

Review Biochemistry & Molecular Biology

Sex-Related Differences in Chronic Myeloid Neoplasms: From the Clinical Observation to the Underlying Biology

Theodoros Karantanos et al.

Summary: Men with chronic myeloid neoplasms have overall worse survival and higher incidence of transformation to acute leukemia, with a male predominance for mutations in high-risk genes. Current research on the genomic profile and sex-related differences in patients with chronic myeloid neoplasms is ongoing, with further investigation needed into the hypothesized biological mechanisms.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Article Hematology

Gender-related differences in the outcomes and genomic landscape of patients with myelodysplastic syndrome/myeloproliferative neoplasm overlap syndromes

Theodoros Karantanos et al.

Summary: Male patients with MDS/MPN have worse outcomes, potentially due to a higher number of somatic mutations, especially in high-risk genes. Further validation in larger cohorts and investigation of underlying mechanisms are warranted.

BRITISH JOURNAL OF HAEMATOLOGY (2021)

Article Medicine, Research & Experimental

Enasidenib drives human erythroid differentiation independently of isocitrate dehydrogenase 2

Ritika Dutta et al.

JOURNAL OF CLINICAL INVESTIGATION (2020)

Review Cell Biology

Molecular Basis for CCRL2 Regulation of Leukocyte Migration

Tiziana Schioppa et al.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2020)

Article Oncology

The Atypical Receptor CCRL2 Is Essential for Lung Cancer Immune Surveillance

Annalisa Del Prete et al.

CANCER IMMUNOLOGY RESEARCH (2019)

Article Biochemistry & Molecular Biology

BloodSpot: a database of healthy and malignant haematopoiesis updated with purified and single cell mRNA sequencing profiles

Frederik Otzen Bagger et al.

NUCLEIC ACIDS RESEARCH (2019)

Review Endocrinology & Metabolism

Mechanistic insights into Regulation of JAK2 Tyrosine Kinase

Stevan R. Hubbard

FRONTIERS IN ENDOCRINOLOGY (2018)

Review Biochemistry & Molecular Biology

The molecular details of cytokine signaling via the JAK/STAT pathway

Rhiannon Morris et al.

PROTEIN SCIENCE (2018)

Article Multidisciplinary Sciences

Characterization and targeting of malignant stem cells in patients with advanced myelodysplastic syndromes

Brett M. Stevens et al.

NATURE COMMUNICATIONS (2018)

Article Medicine, Research & Experimental

Antisense STAT3 inhibitor decreases viability of myelodysplastic and leukemic stem cells

Aditi Shastri et al.

JOURNAL OF CLINICAL INVESTIGATION (2018)

Article Multidisciplinary Sciences

Functional genomic landscape of acute myeloid leukaemia

Jeffrey W. Tyner et al.

NATURE (2018)

Review Oncology

The Use of Flow Cytometry in Myelodysplastic Syndromes: A Review

Laiz Cameirao Bento et al.

FRONTIERS IN ONCOLOGY (2017)

Review Immunology

Atypical Chemokine Receptors and Their Roles in the Resolution of the inflammatory Response

Raffaella Bonecchi et al.

FRONTIERS IN IMMUNOLOGY (2016)

Article Multidisciplinary Sciences

Targeting substrate- site in Jak2 kinase prevents emergence of genetic resistance

Meenu Kesarwani et al.

SCIENTIFIC REPORTS (2015)

Letter Oncology

An MDS xenograft model utilizing a patient-derived cell line

G. W. Rhyasen et al.

LEUKEMIA (2014)

Article Pathology

GCSF-R Expression in Myelodysplastic and Myeloproliferative Disorders and Blast Dysmaturation in CML

Vidya Sagar Hanumanthu et al.

AMERICAN JOURNAL OF CLINICAL PATHOLOGY (2013)

Article Multidisciplinary Sciences

Regulation of human hematopoietic stem cell self-renewal by the microenvironment's control of retinoic acid signaling

Gabriel Ghiaur et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Biochemistry & Molecular Biology

Structural Linkage between Ligand Discrimination and Receptor Activation by Type I Interferons

Christoph Thomas et al.

Article Immunology

Neutropenia with impaired host defense against microbial infection in mice lacking androgen receptor

Kuang-Hsiang Chuang et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2009)

Article Biochemistry & Molecular Biology

Orientational constraints of the gp130 intracellular juxtamembrane domain for signaling

JS Greiser et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)