期刊
EMERGING INFECTIOUS DISEASES
卷 28, 期 2, 页码 323-330出版社
CENTERS DISEASE CONTROL & PREVENTION
DOI: 10.3201/eid2802.210945
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A study found that Burkholderia cepacia complex (BCC) infection occurred in 13 persons who inject drugs in Kowloon West Region, Hong Kong, China. The infection mainly manifested as infective spondylitis, endocarditis, and other serious infections. Pulsed-field gel electrophoresis revealed clonal relatedness among the isolates from 9 patients.
During March 2016-January 2019, Burkholderia cepacia complex (BCC) infection developed in 13 persons who inject drugs (PWID) in Kowloon West Region, Hong Kong, China. Seven cases were infective spondylitis, 2 endocarditis, 2 septic arthritis, 1 intramuscular abscess and bacteremia, and 1 necrotizing fasciitis. Pulsed-field gel electrophoresis revealed that the isolates from 9 patients were clonally related. This clone caused major illness, and 11 of the 13 patients required surgical treatment. Clinicians should be aware of this pathogen and the appropriate broad-spectrum antimicrobial drugs to empirically prescribe for PWID with this life-threatening infection. Close collaboration among public health authorities, outreach social workers, and methadone clinics is essential for timely prevention and control of outbreaks in the PWID population.
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