4.8 Article

Distinct lipid membrane-mediated pathways of Tau assembly revealed by single-molecule analysis

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Cell Biology

Role of the Lipid Membrane and Membrane Proteins in Tau Pathology

Eugene Bok et al.

Summary: Tau accumulation is a pathological hallmark of tauopathies like Alzheimer's disease, with evidence suggesting it spreads through the brain via intercellular transmission and templated misfolding, leading to neurodegeneration and cognitive dysfunction. Recent research is focusing on the interaction of tau with membranes, highlighting the roles of lipids and proteins in both tau secretion and uptake as well as aggregation.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)

Article Chemistry, Multidisciplinary

Conformational Expansion of Tau in Condensates Promotes Irreversible Aggregation

Jitao Wen et al.

Summary: The study reveals that liquid-liquid phase separation of Tau protein leads to conformational changes, resulting in the formation of nanoscale clusters that promote Tau fibrillization. Disease-related mutations P301L and P301S significantly accelerate the fibrillization process of Tau protein.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2021)

Review Cell Biology

Tau and Membranes: Interactions That Promote Folding and Condensation

Chad A. Sallaberry et al.

Summary: Misfolded tau protein is associated with various neurodegenerative diseases, particularly due to electrostatic interactions with anionic cellular membranes and membrane proteins, leading to the formation of reversible condensates and toxic oligomers at the membrane surface. Emerging evidence suggests that polyanionic membranes may serve as a site for phase-separated tau condensation, potentially regulating tau folding/misfolding and directing tau for native membrane-mediated functions.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)

Article Biochemistry & Molecular Biology

Tau-induced mitochondrial membrane perturbation is dependent upon cardiolipin

Angelique Camilleri et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2020)

Article Multidisciplinary Sciences

Exploring the interplay between fibrillization and amorphous aggregation channels on the energy landscapes of tau repeat isoforms

Xun Chen et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

Review Biochemistry & Molecular Biology

Cryo-EM structures of tau filaments

Sjors H. W. Scheres et al.

CURRENT OPINION IN STRUCTURAL BIOLOGY (2020)

Article Chemistry, Physical

Distinct microscopic mechanisms for the accelerated aggregation of pathogenic Tau mutants revealed by kinetic analysis

Qiong-Qiong Yao et al.

PHYSICAL CHEMISTRY CHEMICAL PHYSICS (2020)

Article Biophysics

Polyphosphate Initiates Tau Aggregation through Intra- and Intermolecular Scaffolding

Sanjula P. Wickramasinghe et al.

BIOPHYSICAL JOURNAL (2019)

Article Biochemistry & Molecular Biology

Membrane-mediated fibrillation and toxicity of the tau hexapeptide PHF6

Adeline M. Fanni et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2019)

Article Biochemistry & Molecular Biology

Independent tubulin binding and polymerization by the proline-rich region of tau is regulated by tau's N-terminal domain

Kristen M. McKibben et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2019)

Article Biochemistry & Molecular Biology

Stabilization and Characterization of Cytotoxic Aβ40 Oligomers Isolated from an Aggregation Reaction in the Presence of Zinc Ions

Benedetta Mannini et al.

ACS CHEMICAL NEUROSCIENCE (2018)

Article Biochemistry & Molecular Biology

Membrane-induced initial structure of α-synuclein control its amyloidogenesis on model membranes

Mayu S. Terakawa et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2018)

Article Multidisciplinary Sciences

Discovery and characterization of stable and toxic Tau/phospholipid oligomeric complexes

Nadine Ait-Bouziad et al.

NATURE COMMUNICATIONS (2017)

Review Clinical Neurology

Roles of tau protein in health and disease

Tong Guo et al.

ACTA NEUROPATHOLOGICA (2017)

Review Clinical Neurology

Tau and neurodegenerative disease: the story so far

Khalid Iqbal et al.

NATURE REVIEWS NEUROLOGY (2016)

Review Neurosciences

Tau in physiology and pathology

Yipeng Wang et al.

NATURE REVIEWS NEUROSCIENCE (2016)

Article Biochemistry & Molecular Biology

Polyphosphate: A Conserved Modifier of Amyloidogenic Processes

Claudia M. Cremers et al.

MOLECULAR CELL (2016)

Article Multidisciplinary Sciences

A functional role for intrinsic disorder in the tau-tubulin complex

Ana M. Melo et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)

Article Multidisciplinary Sciences

Structural basis of synaptic vesicle assembly promoted by α-synuclein

Giuliana Fusco et al.

NATURE COMMUNICATIONS (2016)

Article Biochemistry & Molecular Biology

Lipid vesicles trigger α-synuclein aggregation by stimulating primary nucleation

Celine Galvagnion et al.

NATURE CHEMICAL BIOLOGY (2015)

Review Biochemistry & Molecular Biology

The Role of Tau Oligomers in the Onset of Alzheimer's Disease Neuropathology

Maria del Carmen Cardenas-Aguayo et al.

ACS CHEMICAL NEUROSCIENCE (2014)

Review Biochemistry & Molecular Biology

Phosphatidylserine in the brain: Metabolism and function

Hee-Yong Kim et al.

PROGRESS IN LIPID RESEARCH (2014)

Article Multidisciplinary Sciences

The fuzzy coat of pathological human Tau fibrils is a two-layered polyelectrolyte brush

Susanne Wegmann et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Biochemistry & Molecular Biology

Binding of the three-repeat domain of tau to phospholipid membranes induces an aggregated-like state of the protein

Georg Kuenze et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2012)

Article Biochemistry & Molecular Biology

Tau Oligomers Impair Artificial Membrane Integrity and Cellular Viability

Katharina Flach et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2012)

Article Chemistry, Multidisciplinary

Identification of an Aggregation-Prone Structure of Tau

Shana Elbaum-Garfinkle et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)

Article Medicine, Research & Experimental

Biochemistry and Cell Biology of Tau Protein in Neurofibrillary Degeneration

Eva-Maria Mandelkow et al.

COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2012)

Article Neurosciences

Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice

Cristian A. Lasagna-Reeves et al.

MOLECULAR NEURODEGENERATION (2011)

Review Cell Biology

alpha-Synuclein: Membrane Interactions and Toxicity in Parkinson's Disease

Pavan K. Auluck et al.

ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 26 (2010)

Article Biochemistry & Molecular Biology

Functional implications of the association of tau with the plasma membrane

Amy M. Pooler et al.

BIOCHEMICAL SOCIETY TRANSACTIONS (2010)

Article Biophysics

The Role of the Lipid Bilayer in Tau Aggregation

Shana Elbaum-Garfinkle et al.

BIOPHYSICAL JOURNAL (2010)

Article Biochemistry & Molecular Biology

Structural Polymorphism of 441-Residue Tau at Single Residue Resolution

Marco D. Mukrasch et al.

PLOS BIOLOGY (2009)

Article Cell Biology

Tau interacts with Golgi membranes and mediates their association with microtubules

Carole Abi Farah et al.

CELL MOTILITY AND THE CYTOSKELETON (2006)

Article Biochemistry & Molecular Biology

N-terminal fragments of tau inhibit full-length tau polymerization in vitro

Peleg M. Horowitz et al.

BIOCHEMISTRY (2006)

Article Biochemistry & Molecular Biology

Folding of the repeat domain of tau upon binding to lipid surfaces

Patrick Barre et al.

JOURNAL OF MOLECULAR BIOLOGY (2006)

Article Biochemistry & Molecular Biology

Conserved and cooperative assembly of membrane-bound α-helical states of islet amyloid polypeptide

Jefferson D. Knight et al.

BIOCHEMISTRY (2006)

Article Biochemistry & Molecular Biology

Global hairpin folding of tau in solution

S Jeganathan et al.

BIOCHEMISTRY (2006)

Article Biochemistry & Molecular Biology

Triggers of full-length tau aggregation: A role for partially folded interrnediates

CN Chirita et al.

BIOCHEMISTRY (2005)

Article Biochemistry & Molecular Biology

Structure of fully hydrated fluid phase lipid bilayers with monounsaturated chains

N Kucerka et al.

JOURNAL OF MEMBRANE BIOLOGY (2005)

Article Biochemistry & Molecular Biology

Phospholipid catalysis of diabetic amyloid assembly

JD Knight et al.

JOURNAL OF MOLECULAR BIOLOGY (2004)

Article Biochemistry & Molecular Biology

The association of α-synuclein with membranes affects bilayer structure, stability, and fibril formation

M Zhu et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Biochemistry & Molecular Biology

Inhibition of tau polymerization by its carboxy-terminal caspase cleavage fragment

RW Berry et al.

BIOCHEMISTRY (2003)

Article Biochemistry & Molecular Biology

Anionic micelles and vesicles induce tau fibrillization in vitro

CN Chirita et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Biochemistry & Molecular Biology

Tau dephosphorylation at tau-1 site correlates with its association to cell membrane

M Arrasate et al.

NEUROCHEMICAL RESEARCH (2000)