Guanidine Acetic Acid Functionalized Magnetic Nanoparticles: Recoverable Green Catalyst for Transamidation

In the presence of a catalytic amount of Fe3O4-Guanidine acetic acid (GAA) nanoparticles, efficient transamidation of several amides with various amines is described under solvent-free conditions. Fe3O4-Guanidine acetic acid nanoparticles provide the first example of a magnetically recoverable organocatalyst for transamidation in the highest catalytic activity. The catalyst could be simply recycled with the assistance of an external magnet and reused for six runs without significant loss of its catalytic activity.