4.0 Review

A local QSAR model based on the stability of nitrenium ions to support the ICH M7 expert review on the mutagenicity of primary aromatic amines

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Chemistry, Medicinal

Genotoxicity Assessment of Drug Metabolites in the Context of MIST and Beyond

Andreas Zeller et al.

CHEMICAL RESEARCH IN TOXICOLOGY (2020)

Article Medicine, Legal

Management of pharmaceutical ICH M7 (Q)SAR predictions - The impact of model updates

Catrin Hasselgren et al.

REGULATORY TOXICOLOGY AND PHARMACOLOGY (2020)

Article Chemistry, Medicinal

Mechanistic Reactivity Descriptors for the Prediction of Ames Mutagenicity of Primary Aromatic Amines

Lara Kuhnke et al.

JOURNAL OF CHEMICAL INFORMATION AND MODELING (2019)

Article Genetics & Heredity

Meeting report, ICH M7 relevant workshop: use of (Q)SAR systems and expert judgment

Masayuki Mishima et al.

GENES AND ENVIRONMENT (2018)

Article Biochemistry & Molecular Biology

Predicting Aromatic Amine Mutagenicity with Confidence: A Case Study Using Conformal Prediction

Ulf Norinder et al.

BIOMOLECULES (2018)

Article Medicine, Legal

Principles and procedures for implementation of ICH M7 recommended (Q)SAR analyses

Alexander Amberg et al.

REGULATORY TOXICOLOGY AND PHARMACOLOGY (2016)

Article Medicine, Legal

A practical application of two in silico systems for identification of potentially mutagenic impurities

Nigel Greene et al.

REGULATORY TOXICOLOGY AND PHARMACOLOGY (2015)

Article Chemistry, Multidisciplinary

An investigation into pharmaceutically relevant mutagenicity data and the influence on Ames predictive potential

Patrick McCarren et al.

JOURNAL OF CHEMINFORMATICS (2011)

Article Chemistry, Medicinal

An in Silico Method for Predicting Ames Activities of Primary Aromatic Amines by Calculating the Stabilities of Nitrenium Ions

Joerg Bentzien et al.

JOURNAL OF CHEMICAL INFORMATION AND MODELING (2010)

Article Chemistry, Medicinal

LowModeMD-Implicit Low-Mode Velocity Filtering Applied to Conformational Search of Macrocycles and Protein Loops

Paul Labute

JOURNAL OF CHEMICAL INFORMATION AND MODELING (2010)

Review Chemistry, Medicinal

Mutagenicity of nitroaromatic compounds

V Purohit et al.

CHEMICAL RESEARCH IN TOXICOLOGY (2000)