期刊
BIOMATERIALS SCIENCE
卷 10, 期 9, 页码 2122-2153出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/d1bm01974k
关键词
-
资金
- Portuguese Foundation for Science and Technology (FCT) [PTDC/BTM-MAT/30869/2017]
- FCT [2020.01647.CEECIND]
- FCT/MCTES [UIDB/50011/2020, UIDP/50011/2020]
- European Research Council (ERC) [ERC-2014-ADG-669858]
- European Union (EU) [953169]
- Fundação para a Ciência e a Tecnologia [PTDC/BTM-MAT/30869/2017] Funding Source: FCT
Core-shell microcapsules have the potential to recreate the hierarchical structure of biological systems by independently modulating the composition of the core and shell layers. They can be tailored to recreate specific cell niches.
The fabrication of scaffolds that accurately recreate the architecture of living tissues is a major challenge in the field of tissue engineering and regenerative medicine. Core-shell microcapsules hold great potential in this regard, as they can recreate the hierarchical structure of biological systems. The independent modulation of the composition of both core and shell layers allows the design of compartmentalized platforms tailored to the recreation of specific cell niches. Emergent technologies such as superhydrophobic surfaces, microfluidics, electrospray, and layer-by-layer assembly have been successful in producing core-shell microcapsules for the encapsulation of cells and bioactive factors. This review provides an overview of available materials and techniques used in the generation of core-shell microcapsules, while also highlighting some of their potential applications in the design of innovative and effective tissue engineering and regenerative medicine strategies.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据