4.8 Article

Macrophages use apoptotic cell-derived methionine and DNMT3A during efferocytosis to promote tissue resolution

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Cell Biology

Efferocytosis induces macrophage proliferation to help resolve tissue injury

Brennan D. Gerlach et al.

Summary: This study demonstrates that nucleotides derived from apoptotic cell DNA hydrolysis by phagolysosomal DNase2a activate a pathway promoting non-inflammatory macrophage proliferation. The findings suggest that these nucleotides can amplify the resolution benefit by increasing the number of efferocytosing macrophages, thus enhancing tissue resolution in various experimental models including peritonitis, thymocyte apoptosis, and atherosclerosis regression.

CELL METABOLISM (2021)

Review Immunology

Mini-Review: The Administration of Apoptotic Cells for Treating Rheumatoid Arthritis: Current Knowledge and Clinical Perspectives

Eric Toussirot et al.

Summary: Apoptotic cells show therapeutic potential in rheumatoid arthritis by reducing joint inflammation through anti-inflammatory mechanisms, exhibiting synergistic effects when used in combination with conventional medications, and preventing transplant-related complications.

FRONTIERS IN IMMUNOLOGY (2021)

Article Medicine, Research & Experimental

Deficiency of macrophage PHACTR1 impairs efferocytosis and promotes atherosclerotic plaque necrosis

Canan Kasikara et al.

Summary: The rs9349379-G allele is associated with lower levels of PHACTR1 and impaired efferocytosis in macrophages, potentially contributing to CAD risk by compromising the clearance of apoptotic cells in atherosclerotic lesions.

JOURNAL OF CLINICAL INVESTIGATION (2021)

Review Medicine, Research & Experimental

Role of prostaglandin E2 in tissue repair and regeneration

Hui Cheng et al.

Summary: PGE2 plays a crucial role in tissue regeneration by promoting the regeneration of various organ systems through activation of endogenous stem cells, immune regulation, and angiogenesis. Understanding the modulation of tissue regeneration by PGE2 and enhancing its regenerative efficiency are crucial for tissue repair and regeneration processes.

THERANOSTICS (2021)

Article Cell Biology

Macrophage MerTK Promotes Liver Fibrosis in Nonalcoholic Steatohepatitis

Bishuang Cai et al.

CELL METABOLISM (2020)

Article Cardiac & Cardiovascular Systems

Regulatory T Cells License Macrophage Pro-Resolving Functions During Atherosclerosis Regression

Monika Sharma et al.

CIRCULATION RESEARCH (2020)

Review Immunology

Efferocytosis in health and disease

Amanda C. Doran et al.

NATURE REVIEWS IMMUNOLOGY (2020)

Article Medicine, General & Internal

Clearance of apoptotic cells by mesenchymal stem cells contributes to immunosuppression via PGE2

Zhuoya Zhang et al.

EBIOMEDICINE (2019)

Article Multidisciplinary Sciences

Methionine metabolism influences genomic architecture and gene expression through H3K4me3 peak width

Ziwei Dai et al.

NATURE COMMUNICATIONS (2018)

Article Biochemistry & Molecular Biology

Targeting S-adenosylmethionine biosynthesis with a novel allosteric inhibitor of Mat2A

Casey L. Quinlan et al.

NATURE CHEMICAL BIOLOGY (2017)

Article Medicine, General & Internal

Clonal Hematopoiesis and Risk of Atherosclerotic Cardiovascular Disease

S. Jaiswal et al.

NEW ENGLAND JOURNAL OF MEDICINE (2017)

Review Immunology

Pro-Resolving Mediators in Regulating and Conferring Macrophage Function

Jesmond Dalli et al.

FRONTIERS IN IMMUNOLOGY (2017)

Article Cardiac & Cardiovascular Systems

The Role of Efferocytosis in Atherosclerosis

Yoko Kojima et al.

CIRCULATION (2017)

Review Cardiac & Cardiovascular Systems

Macrophage Apoptosis and Efferocytosis in the Pathogenesis of Atherosclerosis

MacRae F. Linton et al.

CIRCULATION JOURNAL (2016)

Article Multidisciplinary Sciences

TAM receptors regulate multiple features of microglial physiology

Lawrence Fourgeaud et al.

NATURE (2016)

Article Multidisciplinary Sciences

MerTK cleavage limits proresolving mediator biosynthesis and exacerbates tissue inflammation

Bishuang Cai et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)

Editorial Material Cardiac & Cardiovascular Systems

Transforming growth factor-: transforming plaque to stability

Kevin Tse et al.

EUROPEAN HEART JOURNAL (2013)

Review Immunology

Multifaceted roles of PGE2 in inflammation and cancer

Masako Nakanishi et al.

SEMINARS IN IMMUNOPATHOLOGY (2013)

Review Gastroenterology & Hepatology

S-adenosylmethionine metabolism and liver disease

Jose M. Mato et al.

ANNALS OF HEPATOLOGY (2013)

Article Cardiac & Cardiovascular Systems

Anti-inflammation Therapy by Activation of Prostaglandin EP4 Receptor in Cardiovascular and Other Inflammatory Diseases

Eva H. C. Tang et al.

JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2012)

Article Multidisciplinary Sciences

Disruption of the 5-lipoxygenase pathway attenuates atherogenesis consequent to COX-2 deletion in mice

Zhou Yu et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Article Immunology

Epigenetic control of macrophage polarization

Osamu Takeuch et al.

EUROPEAN JOURNAL OF IMMUNOLOGY (2011)

Article Multidisciplinary Sciences

Microtubule-associated protein 1 light chain 3 alpha (LC3)-associated phagocytosis is required for the efficient clearance of dead cells

Jennifer Martinez et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Review Biochemistry & Molecular Biology

Cellular and molecular basis for the regulation of inflammation by TGF-beta

Akihiko Yoshimura et al.

JOURNAL OF BIOCHEMISTRY (2010)

Article Cardiac & Cardiovascular Systems

Cyclooxygenase-2 inhibition increases lipopolysaccharide-induced atherosclerosis in mice

Jonathan M. Gitlin et al.

CARDIOVASCULAR RESEARCH (2009)

Article Biochemistry & Molecular Biology

SALL3 Interacts with DNMT3A and Shows the Ability To Inhibit CpG Island Methylation in Hepatocellular Carcinoma

Yuko Shikauchi et al.

MOLECULAR AND CELLULAR BIOLOGY (2009)

Review Cardiac & Cardiovascular Systems

COX-2 inhibitors and cardiovascular risk

Colin D. Funk et al.

JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2007)

Article Biochemistry & Molecular Biology

A novel anti-atherogenic role for COX-2-potential mechanism for the cardiovascular side effects of COX-2 inhibitors

Ajay Narasimha et al.

PROSTAGLANDINS & OTHER LIPID MEDIATORS (2007)

Article Cardiac & Cardiovascular Systems

A novel prostaglandin E receptor 4-associated protein participates in antiinflammatory signaling

K Takayama et al.

CIRCULATION RESEARCH (2006)

Article Biochemistry & Molecular Biology

Prostaglandin E2 suppresses chemokine production in human macrophages through the EP4 receptor

K Takayama et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

Article Hematology

Pathways and regulation of homocysteine metabolism in mammals

JD Finkelstein

SEMINARS IN THROMBOSIS AND HEMOSTASIS (2000)