相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Cyclopropyl Scaffold: A Generalist for Marketed Drugs
Mo-Ran Sun et al.
MINI-REVIEWS IN MEDICINAL CHEMISTRY (2021)
Au-Catalyzed Formal Allylation of Diazo(thio)oxindoles: Application to Tandem Asymmetric Synthesis of Quaternary Stereocenters
Xiao-Yuan Cui et al.
ORGANIC LETTERS (2021)
Traditional Chinese medicine (TCM) as a source of new anticancer drugs
Chang-liang Yao et al.
NATURAL PRODUCT REPORTS (2021)
A highly efficient In(OTf)3-catalyzed [3+3] annulation of spirocyclopropyl oxindoles with 1,4-di-thiane-2,5-diol
Yongjia Hao et al.
CHINESE CHEMICAL LETTERS (2020)
Regiodivergent Intramolecular Nucleophilic Addition of Ketimines for the Diverse Synthesis of Azacycles
Yu-Hui Wang et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)
Design, Synthesis, and Biological Evaluation of Imidazo[1,2-a]pyridine Derivatives as Novel PI3K/mTOR Dual Inhibitors
Ya'nan Yu et al.
JOURNAL OF MEDICINAL CHEMISTRY (2020)
Natural Products as Sources of New Drugs over the Nearly Four Decades from 01/1981 to 09/2019
David J. Newman et al.
JOURNAL OF NATURAL PRODUCTS (2020)
Synthesis and Anticancer Activity of Novel Actinonin Derivatives as HsPDF Inhibitors
Liu Hu et al.
JOURNAL OF MEDICINAL CHEMISTRY (2020)
Opportunities for Tapping into Three-Dimensional Chemical Space through a Quaternary Carbon
Tanaji T. Talele
JOURNAL OF MEDICINAL CHEMISTRY (2020)
Catalytic enantioselective construction of vicinal quaternary carbon stereocenters
Feng Zhou et al.
CHEMICAL SCIENCE (2020)
Catalytic Enantioselective Construction of Spiro Quaternary Carbon Stereocenters
Peng-Wei Xu et al.
ACS CATALYSIS (2019)
Highly enantioselective addition of sulfur-containing heterocycles to isatin-derived ketimines
Michael Franc et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2019)
Quest for Novel Chemical Entities through Incorporation of Silicon in Drug Scaffolds
Remya Ramesh et al.
JOURNAL OF MEDICINAL CHEMISTRY (2018)
Development of Synthetic Methodologies via Catalytic Enantioselective Synthesis of 3,3-Disubstituted Oxindoles
Zhong-Yan Cao et al.
ACCOUNTS OF CHEMICAL RESEARCH (2018)
A C=O center dot center dot center dot Isothiouronium Interaction Dictates Enantiodiscrimination in Acylative Kinetic Resolutions of Tertiary Heterocyclic Alcohols
Mark D. Greenhalgh et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)
Catalytic asymmetric synthesis of spirooxindoles: recent developments
Guang-Jian Mei et al.
CHEMICAL COMMUNICATIONS (2018)
New development in the enantioselective synthesis of spiro compounds
Aishun Ding et al.
CHEMICAL SOCIETY REVIEWS (2018)
Analysis of US FDA-Approved Drugs Containing Sulfur Atoms
Kevin A. Scott et al.
TOPICS IN CURRENT CHEMISTRY (2018)
Catalytic enantioselective synthesis of cyclopropanes featuring vicinal all-carbon quaternary stereocenters with a CH2F group; study of the influence of C-FH-N interactions on reactivity
Zhong-Yan Cao et al.
ORGANIC CHEMISTRY FRONTIERS (2018)
Progress in the medicinal chemistry of silicon: C/Si exchange and beyond
Shinya Fujii et al.
FUTURE MEDICINAL CHEMISTRY (2017)
An enantioselective conjugate addition reaction of 3-substituted benzothiophen-2-ones and 2-phthalimidoacrylates
Shoulei Li et al.
ORGANIC CHEMISTRY FRONTIERS (2017)
Recent Developments in Organoboron Chemistry: Old Dogs, New Tricks
James W. B. Fyfe et al.
CHEM (2017)
Analysis of Past and Present Synthetic Methodologies on Medicinal Chemistry: Where Have All the New Reactions Gone?
Dean G. Brow et al.
JOURNAL OF MEDICINAL CHEMISTRY (2016)
Enantioselective Cyclopropanation of a Wide Variety of Olefins Catalyzed by Ru(II)-Pheox Complexes
Soda Chanthamath et al.
ACCOUNTS OF CHEMICAL RESEARCH (2016)
Synthetic Strategies toward Natural Products Containing Contiguous Stereogenic Quaternary Carbon Atoms
Martin Bueschleb et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2016)
Spirooxindoles as novel 3D-fragment scaffolds: Synthesis and screening against CYP121 from M. tuberculosis
Holly J. Davis et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2016)
The Cyclopropyl Fragment is a Versatile Player that Frequently Appears in Preclinical/Clinical Drug Molecules
Tanaji T. Talele
JOURNAL OF MEDICINAL CHEMISTRY (2016)
Chiral Alkyl Halides: Underexplored Motifs in Medicine
Balint Gal et al.
MARINE DRUGS (2016)
Modern Organic Synthesis with α-Diazocarbonyl Compounds
Alan Ford et al.
CHEMICAL REVIEWS (2015)
Advances in Catalytic Enantioselective Fluorination, Mono-, Di-, and Trifluoromethylation, and Trifluoromethylthiolation Reactions
Xiaoyu Yang et al.
CHEMICAL REVIEWS (2015)
A New Golden Age for Donor-Acceptor Cyclopropanes
Tobias F. Schneider et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2014)
The use of spirocyclic scaffolds in drug discovery
Yajun Zheng et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2014)
Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001-2011)
Jiang Wang et al.
CHEMICAL REVIEWS (2014)
Acid Hydrazides, Potent Reagents for Synthesis of Oxygen-, Nitrogen-, and/or Sulfur-Containing Heterocyclic Rings
Poulomi Majumdar et al.
CHEMICAL REVIEWS (2014)
Four-Membered Ring-Containing Spirocycles: Synthetic Strategies and Opportunities
Erick M. Carreira et al.
CHEMICAL REVIEWS (2014)
Facile regioselective synthesis and antimicrobial activity of heterocycle-phosphor esters
Wafaa M. Abdou et al.
MONATSHEFTE FUR CHEMIE (2014)
Catalytic enantioselective synthesis of quaternary carbon stereocentres
Kyle W. Quasdorf et al.
NATURE (2014)
In situ generation of ion-paired chiral ligands: rapid identification of the optimal ligand for palladium-catalyzed asymmetric allylation
Kohsuke Ohmatsu et al.
CHEMICAL SCIENCE (2014)
Organocatalytic Asymmetric Assembly Reactions: Synthesis of Spirooxindoles via Organocascade Strategies
Daojuan Cheng et al.
ACS CATALYSIS (2014)
Recent Advances in Asymmetric Organocatalytic Construction of 3,3′-Spirocyclic Oxindoles
Liang Hong et al.
ADVANCED SYNTHESIS & CATALYSIS (2013)
Enantioselective Organocatalytic Synthesis of Sulfur-Containing Spirocyclic Compounds
Pierre-Yves Geant et al.
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (2013)
Highly Stereoselective Olefin Cyclopropanation of Diazooxindoles Catalyzed by a C2-Symmetric Spiroketal Bisphosphine/Au(I) Complex
Zhong-Yan Cao et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2013)
DRUG DISCOVERY Diversifying complexity
Indrajeet Sharma et al.
NATURE CHEMISTRY (2013)
A Highly Diastereo- and Enantioselective Hg(II)-Catalyzed Cyclopropanation of Diazooxindoles and Alkenes
Zhong-Yan Cao et al.
ORGANIC LETTERS (2013)
Escape from Flatland 2: complexity and promiscuity
Frank Lovering
MEDCHEMCOMM (2013)
Asymmetric Catalysis for the Synthesis of Spirocyclic Compounds
Annaliese K. Franz et al.
ACS CATALYSIS (2013)
Beyond Size, Ionization State, and Lipophilicity: Influence of Molecular Topology on Absorption, Distribution, Metabolism, Excretion, and Toxicity for Druglike Compounds
Yidong Yang et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
Enantioselective Michael/Cyclization Reaction Sequence: Scaffold-Inspired Synthesis of Spirooxindoles with Multiple Stereocenters
Yiming Cao et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2011)
Transition-Metal-Catalyzed C-S, C-Se, and C-Te Bond Formation via Cross-Coupling and Atom-Economic Addition Reactions
Irina P. Beletskaya et al.
CHEMICAL REVIEWS (2011)
Natural and Synthetic Small Boron-Containing Molecules as Potential Inhibitors of Bacterial and Fungal Quorum Sensing
Valery M. Dembitsky et al.
CHEMICAL REVIEWS (2011)
Asymmetric Construction of Stereogenic Carbon Centers Featuring a Trifluoromethyl Group from Prochiral Trifluoromethylated Substrates
Jing Nie et al.
CHEMICAL REVIEWS (2011)
Improvement in Aqueous Solubility in Small Molecule Drug Discovery Programs by Disruption of Molecular Planarity and Symmetry
Minoru Ishikawa et al.
JOURNAL OF MEDICINAL CHEMISTRY (2011)
Efficient Construction of alpha-Spirocyclopropyl Lactones: Iridium-Salen-Catalyzed Asymmetric Cyclopropanation
Masami Ichinose et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2009)
Heterocycles from cyclopropanes: applications in natural product synthesis
Cheryl A. Carson et al.
CHEMICAL SOCIETY REVIEWS (2009)
Recent studies on the reactions of α-diazocarbonyl compounds
Zhenhua Zhang et al.
TETRAHEDRON (2008)
Fluorine in pharmaceuticals:: Looking beyond intuition
Klaus Mueller et al.
SCIENCE (2007)
Vinyldiazolactone as a vinylcarbene precursor: Highly selective C-H insertion and cyclopropanation reactions
Darren Bykowski et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2006)
Contiguous stereogenic quaternary carbons: A daunting challenge in natural products synthesis
EA Peterson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
分享论文
