期刊
THERANOSTICS
卷 12, 期 6, 页码 2860-2893出版社
IVYSPRING INT PUBL
DOI: 10.7150/thno.70721
关键词
Carbon dots; targeted bioimaging; cancer therapy; nanotheranostic
资金
- National Natural Science Foundation of China [12074348, U2004168, U21A2070]
- China Postdoctoral Science Foundation [2020M6 82310]
- Natural Science Foundation of Henan Province [212300410078]
Carbon dots (CDs), a new class of carbon nanomaterials, have various structures and extraordinary physicochemical properties, making them attractive for their potential applications in targeted bioimaging and therapy in tumor theranostics. CDs have been used as highly efficient imaging agents for photoluminescence bioimaging of tumor cells. With their unique structure and properties, CDs have been integrated into various nanotheranostic strategies for diverse tumors, demonstrating excellent performances in precise targeted bioimaging and therapy. Future prospects and challenges of CDs in promising nanotheranostic strategies are also discussed.
Carbon dots (CDs), as one new class of carbon nanomaterials with various structure and extraordinary physicochemical properties, have attracted tremendous interest for their potential applications in tumor theranostics, especially in targeted bioimaging and therapy. In these areas, CDs and its derivatives have been employed as highly efficient imaging agent for photoluminescence bioimaging of tumors cells. With unique structure, optical and/or dose attention properties, CDs have been harnessed in various nanotheranostic strategies for diverse tumors through integrating with other functional nanoparticles or utilizing their inherent physical properties. Up to now, CDs have been approved as novel biomaterials by their excellent performances in precise targeted bioimaging and therapy for tumors. Herein, the latest progress in the development of CDs in targeted bioimaging and tumor therapy are reviewed. Meanwhile, the challenges and future prospects of the application of CDs in promising nanotheranostic strategies are discussed and proposed.
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