4.0 Article

High quality genome assembly of the anhydrobiotic midge provides insights on a single chromosome-based emergence of extreme desiccation tolerance

期刊

NAR GENOMICS AND BIOINFORMATICS
卷 4, 期 2, 页码 -

出版社

OXFORD UNIV PRESS
DOI: 10.1093/nargab/lqac029

关键词

-

资金

  1. Japan Society for the Promotion of Science (JSPS) KAKENHI [JP18J21155, JP18H02217, JP22128001, JP23128512, JP25128714, JP17H01511, JP16K07308]
  2. Agriculture, Forestry and Fisheries Research Council of the Ministry of Agriculture, Forestry and Fisheries [JPJ008837]
  3. Russian Science Foundation [20-44-07002]
  4. Japan Agency for Medical Research and Development (AMED)
  5. Strategic International Collaborative Research project [JPJ008837]
  6. Russian Science Foundation [20-44-07002] Funding Source: Russian Science Foundation

向作者/读者索取更多资源

The study reveals the distinct functional specialization of Chromosome 4 in the sleeping chironomid for desiccation tolerance genes, as well as the high genetic turnover in this chromosome, enabling midges to rapidly adapt to harsh environments.
Non-biting midges (Chironomidae) are known to inhabit a wide range of environments, and certain species can tolerate extreme conditions, where the rest of insects cannot survive. In particular, the sleeping chironomid Polypedilum vanderplanki is known for the remarkable ability of its larvae to withstand almost complete desiccation by entering a state called anhydrobiosis. Chromosome numbers in chironomids are higher than in other dipterans and this extra genomic resource might facilitate rapid adaptation to novel environments. We used improved sequencing strategies to assemble a chromosome-level genome sequence for P. vanderplanki for deep comparative analysis of genomic location of genes associated with desiccation tolerance. Using whole genome-based cross-species and intra-species analysis, we provide evidence for the unique functional specialization of Chromosome 4 through extensive acquisition of novel genes. In contrast to other insect genomes, in the sleeping chironomid a uniquely high degree of subfunctionalization in paralogous anhydrobiosis genes occurs in this chromosome, as well as pseudogenization in a highly duplicated gene family. Our findings suggest that the Chromosome 4 in Polypedilum is a site of high genetic turnover, allowing it to act as a 'sandbox' for evolutionary experiments, thus facilitating the rapid adaptation of midges to harsh environments.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.0
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据