期刊
JOURNAL OF FOOD AND DRUG ANALYSIS
卷 30, 期 1, 页码 104-110出版社
DIGITAL COMMONS BEPRESS
DOI: 10.38212/2224-6614.3390
关键词
Consumption trend; Opioid; Pain
资金
- Taiwan FDA [109 TFDA-N-010]
This study evaluated the trend of opioid consumption for pain management in Taiwan and compared it with neighboring Asian countries. The findings showed that opioid consumption in Taiwan has slowly increased from 2008 to 2018, with fentanyl and morphine being the most commonly used opioids. Compared with neighboring Asian countries, Taiwan's opioid consumption level was between Japan and Singapore.
Opioids are effective analgesics for pain relief, however, inappropriate use may cause risks. The aims of the study were to evaluate trends of opioid consumption for pain management in Taiwan and compare them among neighboring Asian countries. Opioid consumption data, including fentanyl, morphine, oxycodone, hydromorphone, codeine, and pethidine, were collected from the Controlled Drugs Management Information System of Taiwan Food and Drug Administration from 2008 to 2018. Data of different continents and neighboring Asian countries were retrieved from the WHO website. The major findings include: (1) In Taiwan, the total annual opioid consumption has gradually increased from 2008 to 2018, with fentanyl being the most frequently consumed opioid analgesic, followed by morphine. Codeine and pethidine consumption dropped significantly over the years. (2) In neighboring Asian countries, the opioid consumption in order from highest to lowest consumption were South Korea, Japan, Taiwan, Singapore, Hong Kong (China), and China. We concluded that, from 2008 to 2018, the total opioid consumption trend for pain management in Taiwan has slowly increased, with fentanyl and morphine being the most commonly used opioids. When compared with neighboring Asian countries, level of opioid consumption in Taiwan was between Japan and Singapore. The research results may provide a reference for healthcare professionals worldwide.
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