Multi-collector Inductively Coupled Plasma Mass Spectrometry: New Developments and Basic Concepts for High-precision Measurements of Mass- dependent Isotope Signatures

Due to the development of multi-collector inductively coupled plasma mass spectrometry (MC-ICPMS) around 25 years ago, the isotopic compositions of a large range of elements (masses from Li to U) are now analyzed with high enough precision and accuracy to resolve subtle natural variations. These so-called 'nontraditional stable isotope systems' opened many new research avenues and are applied at an increasing rate in industry and research projects and in a broad range of different disciplines, including archeology, biology, physics, cosmochemistry and geology. Here, we briefly summarize the most basic concepts of MC-ICP-MS, introduce new technical developments and address important points on how to acquire accurate high-precision isotope measurements of non-traditional stable isotopes.

Automated summary

The development of multi-collector inductively coupled plasma mass spectrometry (MC-ICPMS) allows for high precision and accurate analysis of isotopic compositions of a wide range of elements. This technique has opened up new research avenues and is increasingly applied in various disciplines.