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Gpbar1 agonism promotes a Pgc-1α-dependent browning of white adipose tissue and energy expenditure and reverses diet-induced steatohepatitis in mice
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Vertical sleeve gastrectomy activates GPBAR-1/TGR5 to sustain weight loss, improve fatty liver, and remit insulin resistance in mice
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Gut Microbiota Orchestrates Energy Homeostasis during Cold
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JOURNAL OF LIPID RESEARCH (2014)
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CELL METABOLISM (2013)
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MOLECULAR ENDOCRINOLOGY (2012)
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CELL METABOLISM (2009)
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JOURNAL OF LIPID RESEARCH (2009)
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JOURNAL OF CLINICAL INVESTIGATION (2006)
Targeted disruption of G protein-coupled bile acid receptor 1 (Gpbar1/M-Bar) in mice
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Targeted deletion of Gpbar1 protects mice from cholesterol gallstone formation
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JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation
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JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Identification of membrane-type receptor for bile acids (M-BAR)
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6α-ethyl-chenodeoxycholic acid (6-ECDCA), a potent and selective FXR agonist endowed with anticholestatic activity
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JOURNAL OF MEDICINAL CHEMISTRY (2002)
A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis
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