4.6 Article

Photoredox-catalyzed fluorodifluoroacetylation of alkenes with FSO2CF2CO2Me and Et3N•3HF

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ORGANIC & BIOMOLECULAR CHEMISTRY
卷 20, 期 18, 页码 3726-3730

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ROYAL SOC CHEMISTRY
DOI: 10.1039/d2ob00488g

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  1. National Natural Science Foundation of China [21871163, 22071134, 21911530097]

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A photoredox-catalyzed three-component fluorodifluoroacetylation of aromatic alkenes is reported, showcasing a broad substrate scope and tolerance towards functional groups. One advantage of the reaction is the utilization of a nucleophilic fluoride source and a general difluoroacetylation reagent for the fluorodifluoroacetylation of alkenes.
Photoredox-catalyzed three-component fluorodifluoroacetylation of aromatic alkenes is reported, which features a wide substrate scope and functional group tolerance. An advantage of the reaction is the use of a nucleophilic fluoride source and a general difluoroacetylation reagent for the fluorodifluoroacetylation of alkenes.

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