Recent trends in chemistry, structure, and various applications of 1-acyl-3-substituted thioureas: a detailed review

The interest in acyl thioureas has continually been escalating owing to their extensive applications in diverse fields, such as synthetic precursors of new heterocycles, pharmacological and materials science, and technology. These scaffolds exhibit a wide variety of biological activities such as antitumor, enzyme inhibitory, anti-bacterial, anti-fungal, and anti-malarial activities and find utilization as chemosensors, adhesives, flame retardants, thermal stabilizers, antioxidants, polymers and organocatalysts. In addition, the synthesis, and applications of coordination complexes of these ligands have also been overviewed. The current review is a continuation of our previous efforts in this area, focusing on the recent advancements during the period 2017 to present.

Automated summary

The interest in acyl thioureas has been continuously increasing due to their extensive applications and diverse biological activities. This review focuses on the recent advancements in the synthesis, applications, and coordination complexes of these ligands from 2017 to present.