Differentiation Epitopes Define Hematopoietic Stem Cells and Change with Cell Cycle Passage

Hematopoietic stem cells express differentiation markers B220 and Gr1 and are proliferative. We have shown that the expression of these entities changes with cell cycle passage. Overall, we conclude that primitive hematopoietic stem cells alter their differentiation potential with cell cycle progression.

Automated summary

It has been demonstrated that hematopoietic stem cells alter the expression of differentiation markers B220 and Gr1 with cell cycle progression, indicating changes in their differentiation potential.