期刊
ACS BIOMATERIALS SCIENCE & ENGINEERING
卷 3, 期 7, 页码 1417-1425出版社
AMER CHEMICAL SOC
DOI: 10.1021/acsbiomaterials.6b00597
关键词
nanomaterial; antimicrobial; nanosafety; electron microscopy; XPS; ICP-MS; nano particle release
资金
- MIUR [PON01_02210]
- Regione Puglia [56]
Silver nanophases are routinely used as bioactive additives in commercial products. Besides their antimicrobial activity, nanosafety issues regarding the application of (silver-based) nanoantimicrobials should be considered, as well. In this study, we modified polyurethane foams, typically employed in air filtration and stuffing, by photodeposited silver nanoparticles for preparing hybrid materials (Ag-PU) with antibacterial properties. The composite materials were characterized in terms of morphology, surface chemical composition, ionic release in contact media, bioactivity, as well as whole nanopartide release. Cytocompatibility was also assessed on 3T3 mouse fibroblasts. The proposed systematic approach allows for defining suitable composite final properties, in terms of bioactivity and safety, by properly tuning the deposition parameters.
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