Study on the Secondary Metabolites of Endophytic Penicillium sclerotiorum HLL113

Article Chemistry, Applied

Reactive oxygen species altering the metabolite profile of the marine-derived fungus Dichotomomyces cejpii F31-1

Sharpkate Shaker et al.

Summary: The addition of hydrogen peroxide to the culture medium of marine-derived fungus resulted in changes in the secondary metabolites, with some compounds showing cytotoxic activity against human prostate cancer cells.

NATURAL PRODUCT RESEARCH (2021)

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Review Biochemistry & Molecular Biology

Marine Natural Products: the Important Resource of Biological Insecticide

Chenggang Song et al.

Summary: Marine habitats harbor a rich diversity of biological resources, including marine plants, animals, and microorganisms. Marine natural products with diverse structures and insecticidal activity have broad applications for future research in agriculture and health.

CHEMISTRY & BIODIVERSITY (2021)

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Article Biochemistry & Molecular Biology

Five New Triene Derivatives from the Fungus Penicillium herquei JX4

Ze-Wu Luo et al.

Summary: Five undescribed triene derivatives and one known compound were isolated from the mangrove endophytic fungus, Penicillium herquei JX4. The structures of these compounds were elucidated using various spectroscopic methods, and their absolute configurations were confirmed by comparing experimental or calculated ECD spectra. Two of the compounds showed inhibitory activities against LPS-induced NO production.

CHEMISTRY & BIODIVERSITY (2021)

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Review Biochemistry & Molecular Biology

Marine Natural Products as a Source of Drug Leads against Respiratory Viruses: Structural and Bioactive Diversity

Tian-Tian Sun et al.

Summary: Respiratory viruses, such as influenza virus, respiratory syncytial virus, and coronavirus, pose serious threats to human health. Marine organisms are important for discovering effective drugs against these viruses, as they can produce secondary metabolites with novel structures and diverse biological activities. This review discusses the structures and antiviral activities of 167 marine-derived secondary metabolites against respiratory viruses from 1981 to 2019, citing 102 references.

CURRENT MEDICINAL CHEMISTRY (2021)

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Article Plant Sciences

Austins-Type Meroterpenoids from a Mangrove-Derived Penicillium sp.

Meng Bai et al.

Summary: Three unusual austins-type meroterpenoids were isolated from a mangrove-derived fungus, each with unique structural features. These compounds showed inhibitory effects on the growth of Helicoverpa armigera larvae.

JOURNAL OF NATURAL PRODUCTS (2021)

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Article Chemistry, Applied