期刊
PATHOPHYSIOLOGY
卷 29, 期 2, 页码 223-232出版社
MDPI
DOI: 10.3390/pathophysiology29020018
关键词
cannabis; propofol; hypersalivation; sedation
类别
Legalization/decriminalization of cannabis may lead to more patients with recent exposure to cannabis, but little is known about its interactions with Propofol anesthesia. This study presents three cases of 'cannabis-induced hypersalivation after propofol' (CHAP) and evaluates management options.
Legalization/decriminalization of cannabis will increase the numbers of patients who have had recent exposure to recreational or medical cannabis. Currently, little has been reported about potential interactions between cannabis use and Propofol anesthesia e.g., for oropharyngeal procedures. We describe three cases of 'cannabis-induced hypersalivation after propofol' (CHAP) and present our institutions' experience with this unique pharmacological combination. Increased hypersalivation may complicate procedures and represent a procedural risk of suffocation. We evaluate possible pharmacological interactions that might underlie this phenomenon and consider management options going forward.
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