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Prediction of non-recovery from ventilator-demanding acute respiratory failure, ARDS and death using lung damage biomarkers: data from a 1200-patient critical care randomized trial
Jens-Ulrik S. Jensen et al.
ANNALS OF INTENSIVE CARE (2016)
Redox mechanisms in age-related lung fibrosis
Ashish Kurundkar et al.
REDOX BIOLOGY (2016)
Clemastine Confers Neuroprotection and Induces an Anti-Inflammatory Phenotype in SOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis
Savina Apolloni et al.
MOLECULAR NEUROBIOLOGY (2016)
Neuroprotective effect of ebselen against intracerebroventricular streptozotocin-induced neuronal apoptosis and oxidative stress in rats
Cuneyt Unsal et al.
TOXICOLOGY AND INDUSTRIAL HEALTH (2016)
Airway smooth muscle NOX4 is upregulated and modulates ROS generation in COPD
Fay Hollins et al.
RESPIRATORY RESEARCH (2016)
NOX Modifiers-Just a Step Away from Application in the Therapy of Airway Inflammation?
Joanna Wieczfinska et al.
ANTIOXIDANTS & REDOX SIGNALING (2015)
Autophagy and oxidative stress in cardiovascular diseases
Yu Mei et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2015)
Post-treatment with an ultra-low dose of NADPH oxidase inhibitor diphenyleneiodonium attenuates disease progression in multiple Parkinson's disease models
Qingshan Wang et al.
BRAIN (2015)
Pulmonary Artery Enlargement Is Associated With Right Ventricular Dysfunction and Loss of Blood Volume in Small Pulmonary Vessels in Chronic Obstructive Pulmonary Disease
J. Michael Wells et al.
Circulation-Cardiovascular Imaging (2015)
Nox and renal disease
Chet E. Holterman et al.
CLINICAL SCIENCE (2015)
Role of NADPH oxidase in the regulation of autophagy in cardiomyocytes
Sebastiano Sciarretta et al.
CLINICAL SCIENCE (2015)
Nox Inhibitors & Therapies: Rational Design of Peptidic and Small Molecule Inhibitors
M. Eugenia Cifuentes-Pagano et al.
CURRENT PHARMACEUTICAL DESIGN (2015)
Damage-associated molecular pattern-activated neutrophil extracellular trap exacerbates sterile inflammatory liver injury
Hai Huang et al.
HEPATOLOGY (2015)
Incidence and Outcomes of Acute Respiratory Distress Syndrome A Nationwide Registry-Based Study in Taiwan, 1997 to 2011
Wei Chen et al.
MEDICINE (2015)
P2X7 receptor is critical in α-synuclein-mediated microglial NADPH oxidase activation
Tianfang Jiang et al.
NEUROBIOLOGY OF AGING (2015)
Ethanol directly induced HMGB1 release through NOX2/NLRP1 inflammasome in neuronal cells
Xiaolan Wang et al.
TOXICOLOGY (2015)
Apocynin suppression of NADPH oxidase reverses the aging process in mesenchymal stem cells to promote osteogenesis and increase bone mass
Jinlong Sun et al.
SCIENTIFIC REPORTS (2015)
NOX signaling in molecular cardiovascular mechanisms involved in the blood pressure homeostasis
Mariarosaria Santillo et al.
FRONTIERS IN PHYSIOLOGY (2015)
Reciprocal regulation of TGF-β and reactive oxygen species: A perverse cycle for fibrosis
Rui-Ming Liu et al.
REDOX BIOLOGY (2015)
NADPH oxidases: an overview from structure to innate immunity-associated pathologies
Arvind Panday et al.
CELLULAR & MOLECULAR IMMUNOLOGY (2015)
Free Radicals: Properties, Sources, Targets, and Their Implication in Various Diseases
Alugoju Phaniendra et al.
INDIAN JOURNAL OF CLINICAL BIOCHEMISTRY (2015)
Nox2-dependent glutathionylation of endothelial NOS leads to uncoupled superoxide production and endothelial barrier dysfunction in acute lung injury
Feng Wu et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2014)
An Inhibitor of NADPH Oxidase-4 Attenuates Established Pulmonary Fibrosis in a Rodent Disease Model
Elizabeth R. Jarman et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2014)
A translational preclinical model of interstitial pulmonary fibrosis and pulmonary hypertension: mechanistic pathways driving disease pathophysiology
Elizabeth R. Jarman et al.
PHYSIOLOGICAL REPORTS (2014)
Ethers and esters derived from apocynin avoid the interaction between p47phox and p22phox subunits of NADPH oxidase: evaluation in vitro and in silico
Martha Edith Macias-Perez et al.
BIOSCIENCE REPORTS (2013)
Diphenyleneiodonium protects preoligodendrocytes against endotoxin-activated microglial NADPH oxidase-generated peroxynitrite in a neonatal rat model of periventricular leukomalacia
Ya-fang He et al.
BRAIN RESEARCH (2013)
NOX2 Protects against Prolonged Inflammation, Lung Injury, and Mortality following Systemic Insults
Laura C. Whitmore et al.
JOURNAL OF INNATE IMMUNITY (2013)
Apocynin: Chemical and Biophysical Properties of a NADPH Oxidase Inhibitor
Maicon S. Petronio et al.
MOLECULES (2013)
Natural Compounds as Modulators of NADPH Oxidases
Tullia Maraldi
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2013)
Rational Design of Small Molecule Inhibitors Targeting the Rac GTPase-p67Phox Signaling Axis in Inflammation
Emily E. Bosco et al.
CHEMISTRY & BIOLOGY (2012)
Consensus in silico computational modelling of the p22phox subunit of the NADPH oxidase
Daniel N. Meijles et al.
COMPUTATIONAL BIOLOGY AND CHEMISTRY (2012)
Glucose-6-phosphate dehydrogenase, NADPH, and cell survival
Robert C. Stanton
IUBMB LIFE (2012)
Physiological Roles of Mitochondrial Reactive Oxygen Species
Laura A. Sena et al.
MOLECULAR CELL (2012)
Serine Protease Inhibitor Attenuates Ovalbumin Induced Inflammation in Mouse Model of Allergic Airway Disease
Sanjay Saw et al.
PLOS ONE (2012)
A Key Role for NOX4 in Epithelial Cell Death During Development of Lung Fibrosis
Stephanie Carnesecchi et al.
ANTIOXIDANTS & REDOX SIGNALING (2011)
NOX1, 2, 4, 5: counting out oxidative stress
K. Wingler et al.
BRITISH JOURNAL OF PHARMACOLOGY (2011)
Nox2 B-loop peptide, Nox2ds, specifically inhibits the NADPH oxidase Nox2
Gabor Csanyi et al.
FREE RADICAL BIOLOGY AND MEDICINE (2011)
Pathogen Recognition by the Innate Immune System
Himanshu Kumar et al.
INTERNATIONAL REVIEWS OF IMMUNOLOGY (2011)
Delayed inflammatory mRNA and protein expression after spinal cord injury
Kimberly R. Byrnes et al.
JOURNAL OF NEUROINFLAMMATION (2011)
Estimation of Oxidative Stress Markers in Chronic Kidney Disease
Agnieszka Kuchta et al.
KIDNEY & BLOOD PRESSURE RESEARCH (2011)
NAD(P)H Oxidase Mediates TGF-beta 1-Induced Activation of Kidney Myofibroblasts
Corry D. Bondi et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2010)
Post-Stroke Inhibition of Induced NADPH Oxidase Type 4 Prevents Oxidative Stress and Neurodegeneration
Christoph Kleinschnitz et al.
PLOS BIOLOGY (2010)
p47phox, the phagocyte NADPH oxidase/NOX2 organizer: structure, phosphorylation and implication in diseases
Jamel El-Benna et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2009)
Role of extracellular superoxide in neutrophil activation: interactions between xanthine oxidase and TLR4 induce proinflammatory cytokine production
Emmanuel Lorne et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2008)
Oxidative stress and covalent modification of protein with bioactive aldehydes
Paul A. Grimsrud et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Diphenyleneiodonium and dimethylsulfoxide for treatment of reperfusion injury in cerebral ischemia of the rat
Simon Nagel et al.
BRAIN RESEARCH (2007)
The NOX family of ROS-generating NADPH oxidases: Physiology and pathophysiology
Karen Bedard et al.
PHYSIOLOGICAL REVIEWS (2007)
Advanced glycation end products - Sparking the development of diabetic vascular injury
Alison Goldin et al.
CIRCULATION (2006)
Novel Nox inhibitor VAS2870 attenuates PDGF-dependent smooth muscle cell chemotaxis, but not proliferation
Henrik ten Freyhaus et al.
CARDIOVASCULAR RESEARCH (2006)
The NADPH oxidase Nox3 constitutively produces superoxide in a p22Phox-dependent manner
N Ueno et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Ebselen, a seleno-organic antioxidant, is neuroprotective after embolic strokes in rabbits - Synergism with low-dose tissue plasminogen activator
PA Lapchak et al.
STROKE (2003)