3.8 Article

Phytochemical screening of Nelatangedu, Senna alexandrina L. by FTIR and GC-MS

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ANADOLU UNIV
DOI: 10.9756/INT-JECSE/V14I3.307

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Senna alexandrina; phytochemical compounds; FTIR; GC-MS

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The leaves and pods of Senna alexandrina plant have been used in traditional medicine for their medicinal properties. The extracts of these plant parts contain compounds with laxative and therapeutic effects. In this study, the phytochemical composition of Senna alexandrina extracts was analyzed using FTIR and GC-MS techniques. The analysis revealed the presence of various compounds with medicinal properties, such as anti-tumor, nephroprotective, laxative, antioxidant, neuroprotective, anti-cancer, and pesticidal activities.
Senna alexandrina leaves and pods are utilized in seasonal medication since precedent days. In ancient lore, healthful herbs play a major role within the hindrance and treatment of microorganism diseases. The pods and leaves extracts of this plant contain anthraquinone glycosides that have a major laxative result. Within the gift study, the phytochemical screening of bush plant extracts was met out by FTIR and GC-MS. The NIST Ver. 2.0 of 2005 library was referenced for the detection of the compounds and their bioactivity was assessed supported by Duke's Phytochemical and Ethnobotanical Databases. The detection of different compounds like alcohols, phenols, acid, alkanes, primary and secondary amines, and amides, sulfones, sulfonyl chlorides, fluorides, ethers, esters, and anhydrides were confirmed from the spectra of FTIR analysis. The GC-MS analysis offer completely different peaks bearing on thirty-four phytochemicals possessing different medicinal values. These compounds were reportable to point out totally different biological activities like a metastatic tumor (pancreas, pharynx, prostate), Nephroprotective, laxative, inhibitor, neuroprotective, growth (Breast, lung, prostate), and curative (Pesticides, poison gas).

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