3.8 Article

IS DRUG ADHERENCE IN HYPOTHYROIDISM TREATMENT STILL A PROBLEM?

期刊

NOBEL MEDICUS
卷 18, 期 1, 页码 33-38

出版社

NOBEL ILAC

关键词

Therapeutic adherence and compliance; hypothyroidism; treatment failure

向作者/读者索取更多资源

Despite low treatment adherence among most patients with hypothyroidism, the proportion of patients with TSH levels in the normal range is high. Low education level, low socioeconomic status, comorbidities, and multiple drug use are associated with low treatment adherence.
Objective: Although hypothyroidism is a common disease and its treatment is well defined, many patients do not have normal thyroid-stimulating hormone (TSH) levels. Understanding barriers and determinants of treatment adherence help to increase the success of the treatment. Material and Method: This observational cross-sectional study was conducted at the outpatient clinics for Endocrinology and Internal Medicine. We administered a descriptive questionnaire and the 8-item Morisky Medication Adherence Scale consecutively by face-to-face interview method to 490 hypothyroid adult patients in outpatient clinics. Results: The mean age of the patients was 49.3 +/- 13.6 years and 459 (93.7%) of them were female. The mean duration of hypothyroidism was 8.3 +/- 7.9 years. The mean medication adherence score was 2.9 +/- 1.2. Ninety-four-point-seven percent of patients (n=464) were in the low adherence group, 5.1% (n=23) of patients were in the average adherence group, and only one patient (0.2%) was in the high adherence group Thirty-seven-point-four percent of patients had TSH levels out of the normal range. Patients with TSH levels out of the normal range and patients with normal TSH levels had similar treatment adherence levels. Conclusion: Despite the low treatment adherence of most patients with hypothyroidism, the ratio of patients with TSH levels in the normal range is high. The low education level, low socioeconomic status, comorbidities, and multiple drug use are associated with low treatment adherence.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

3.8
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据