相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。HDAC Inhibition Reverses Preexisting Diastolic Dysfunction and Blocks Covert Extracellular Matrix Remodeling
Joshua G. Travers et al.
CIRCULATION (2021)
Therapeutic inhibition of RBM20 improves diastolic function in a murine heart failure model and human engineered heart tissue
Michael H. Radke et al.
SCIENCE TRANSLATIONAL MEDICINE (2021)
Nicotinamide for the treatment of heart failure with preserved ejection fraction
Mahmoud Abdellatif et al.
SCIENCE TRANSLATIONAL MEDICINE (2021)
Scriptaid/exercise-induced lysine acetylation is another type of posttranslational modification occurring in titin
Song Huang et al.
JOURNAL OF APPLIED PHYSIOLOGY (2020)
Site-specific acetyl-mimetic modification of cardiac troponin I modulates myofilament relaxation and calcium sensitivity
Ying H. Lin et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2020)
HDAC inhibition improves cardiopulmonary function in a feline model of diastolic dysfunction
Markus Wallner et al.
SCIENCE TRANSLATIONAL MEDICINE (2020)
Posttranslational modifications of titin from cardiac muscle: how, where, and what for?
Franziska Koser et al.
FEBS JOURNAL (2019)
Titin Gene and Protein Functions in Passive and Active Muscle
Wolfgang A. Linke
ANNUAL REVIEW OF PHYSIOLOGY, VOL 80 (2018)
Diabetes-Induced Cardiomyocyte Passive Stiffening Is Caused by Impaired Insulin-Dependent Titin Modification and Can Be Modulated by Neuregulin-1
Anna-Eliane Hopf et al.
CIRCULATION RESEARCH (2018)
Inhibition of HDAC6 Activity Alleviates Myocardial Ischemia/Reperfusion Injury in Diabetic Rats: Potential Role of Peroxiredoxin 1 Acetylation and Redox Regulation
Yan Leng et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2018)
Drug discovery with an RBM20 dependent titin splice reporter identifies cardenolides as lead structures to improve cardiac filling
Martin Liss et al.
PLOS ONE (2018)
Histone deacetylase activity governs diastolic dysfunction through a nongenomic mechanism
Mark Y. Jeong et al.
SCIENCE TRANSLATIONAL MEDICINE (2018)
HDAC6 inhibition protects cardiomyocytes against doxorubicin-induced acute damage by improving alpha-tubulin acetylation
Rui Song et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2018)
Vericiguat in patients with worsening chronic heart failure and preserved ejection fraction: results of the SOluble guanylate Cyclase stimulatoR in heArT failurE patientS with PRESERVED EF (SOCRATES-PRESERVED) study
Burkert Pieske et al.
EUROPEAN HEART JOURNAL (2017)
Abnormal contractility in human heart myofibrils from patients with dilated cardiomyopathy due to mutations in TTN and contractile protein genes
Petr G. Vikhorev et al.
SCIENTIFIC REPORTS (2017)
Myocardial Stiffness in Patients With Heart Failure and a Preserved Ejection Fraction Contributions of Collagen and Titin
Michael R. Zile et al.
CIRCULATION (2015)
HDAC6 contributes to pathological responses of heart and skeletal muscle to chronic angiotensin-II signaling
Kimberly M. Demos-Davies et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2014)
Tubulin hyperacetylation is adaptive in cardiac proteotoxicity by promoting autophagy
Patrick M. McLendon et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
The physiological roles of histone deacetylase (HDAC) 1 and 2: complex co-stars with multiple leading parts
Richard D. W. Kelly et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2013)
Effect of Phosphodiesterase-5 Inhibition on Exercise Capacity and Clinical Status in Heart Failure With Preserved Ejection Fraction A Randomized Clinical Trial
Margaret M. Redfield et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2013)
Development and Therapeutic Implications of Selective Histone Deacetylase 6 Inhibitors
Jay H. Kalin et al.
JOURNAL OF MEDICINAL CHEMISTRY (2013)
The Cardiac Acetyl-Lysine Proteome
D. Brian Foster et al.
PLOS ONE (2013)
Low Myocardial Protein Kinase G Activity in Heart Failure With Preserved Ejection Fraction
Loek van Heerebeek et al.
CIRCULATION (2012)
Increased myofilament Ca2+ sensitivity and diastolic dysfunction as early consequences of Mybpc3 mutation in heterozygous knock-in mice
Bodvael Fraysse et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2012)
RBM20, a gene for hereditary cardiomyopathy, regulates titin splicing
Wei Guo et al.
NATURE MEDICINE (2012)
Proteomic Analysis of Lysine Acetylation Sites in Rat Tissues Reveals Organ Specificity and Subcellular Patterns
Alicia Lundby et al.
CELL REPORTS (2012)
Cardiac HDAC6 catalytic activity is induced in response to chronic hypertension
Douglas D. Lemon et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2011)
Truncation of Titin's Elastic PEVK Region Leads to Cardiomyopathy With Diastolic Dysfunction
Henk L. Granzier et al.
CIRCULATION RESEARCH (2009)
Protein Kinase G Modulates Human Myocardial Passive Stiffness by Phosphorylation of the Titin Springs
Martina Krueger et al.
CIRCULATION RESEARCH (2009)
PKC Phosphorylation of Titin's PEVK Element A Novel and Conserved Pathway for Modulating Myocardial Stiffness
Carlos Hidalgo et al.
CIRCULATION RESEARCH (2009)
Hypophosphorylation of the Stiff N2B Titin Isoform Raises Cardiomyocyte Resting Tension in Failing Human Myocardium
Attila Borbely et al.
CIRCULATION RESEARCH (2009)
Left Ventricular Function and Exercise Capacity
Jasmine Grewal et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2009)
Mice lacking histone deacetylase 6 have hyperacetylated tubulin but are viable and develop normally
Yu Zhang et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
Tension generation and relaxation in single myofibrils from human atrial and ventricular myocardium
Nicoletta Piroddi et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2007)
Characterization of the two catalytic domains in histone deacetylase 6
H Zou et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Two catalytic domains are required for protein deacetylation
Y Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Sarcomeric determinants of striated muscle relaxation kinetics
C Poggesi et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2005)
Developmentally regulated switching of titin size alters myofibrillar stiffness in the perinatal heart
CA Opitz et al.
CIRCULATION RESEARCH (2004)
Developmental control of titin isoform expression and passive stiffness in fetal and neonatal myocardium
S Lahmers et al.
CIRCULATION RESEARCH (2004)
Altered titin expression, myocardial stiffness, and left ventricular function in patients with dilated cardiomyopathy
SF Nagueh et al.
CIRCULATION (2004)
Titin isoform changes in rat myocardium during development
CM Warren et al.
MECHANISMS OF DEVELOPMENT (2004)
Passive stiffness changes caused by upregulation of compliant titin isoforms in human dilated cardiomyopathy hearts
I Makarenko et al.
CIRCULATION RESEARCH (2004)
Domain-selective small-molecule inhibitor of histone deacetylase 6 (HDAC6)-mediated tubulin deacetylation
SJ Haggarty et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase
BJ North et al.
MOLECULAR CELL (2003)
In vivo destabilization of dynamic microtubules by HDAC6-mediated deacetylation
A Matsuyama et al.
EMBO JOURNAL (2002)
Protein kinase A phosphorylates titin's cardiac-specific N2B domain and reduces passive tension in rat cardiac myocytes
R Yamasaki et al.
CIRCULATION RESEARCH (2002)
Length dependence of tension generation in rat skinned cardiac muscle - Role of titin in the Frank-Starling mechanism of the heart
N Fukuda et al.
CIRCULATION (2001)
Titin-based modulation of calcium sensitivity of active tension in mouse skinned cardiac myocytes
O Cazorla et al.
CIRCULATION RESEARCH (2001)
分享论文
