4.7 Review

Current Understanding of Hydrogel for Drug Release and Tissue Engineering

期刊

GELS
卷 8, 期 5, 页码 -

出版社

MDPI
DOI: 10.3390/gels8050301

关键词

responsive hydrogels; drug release; tissue engineering; synthetic polymer; natural polymer

资金

  1. improvement project of the basic scientific research capacity of young and middle-aged teachers in Guangxi universities [2022KY0565]
  2. scientific research start-up fund for high-level talents of Yulin Normal University [G2022ZK02]

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This review introduces the wide applications of hydrogels in the field of biomedicine, including drug delivery and tissue regeneration. It covers the characteristics and crosslinking methods of natural and synthetic hydrogels, as well as the design and principle of intelligent hydrogels for drug release. The review also discusses the applications, limitations, and research directions of hydrogels in drug release and tissue engineering.
Due to their good absorption, satisfactory biocompatibility, and high safety, hydrogels have been widely used in the field of biomedicine, including for drug delivery and tissue regeneration. In this review, we introduce the characteristics and crosslinking methods of natural and synthetic hydrogels. Then, we highlight the design and principle of intelligent hydrogels (i.e., responsive hydrogels) used for drug release. Moreover, we introduce the application of the application of hydrogels in drug release and tissue engineering, and the limitations and research directions of hydrogel in drug release and tissue engineering are also considered. We hope that this review can provide a reference for follow-up studies in related fields.

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