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In Reply to PAPP-A Results Cannot Be Used to Accurately Estimate Gestational Age

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Article Medical Laboratory Technology

Analytical Comparison of Pregnancy-Associated Plasma Protein-A (PAPP-A) Immunoassays for Biochemical Determination of Gestational Age

Irina A. Buhimschi et al.

Summary: This study compared the technical characteristics of 4 commercially available PAPP-A immunoassays and tested 120 maternal serum samples to establish cutoff values at 70 days GA. The results showed that all immunoassays had sensitivities and specificities >= 80%, but there were differences in PAPP-A values depending on the immunoassay used.

JOURNAL OF APPLIED LABORATORY MEDICINE (2021)

Article Obstetrics & Gynecology

Sensitivity and specificity of placental proteins for gestational age screening: An exploratory study

Elizabeth G. Raymond et al.

CONTRACEPTION (2020)