期刊
AGING AND DISEASE
卷 13, 期 2, 页码 402-422出版社
INT SOC AGING & DISEASE
DOI: 10.14336/AD.2021.1210
关键词
COVID-19; SARS-CoV-2 variants; mutation; VOC; VOI; VUM
资金
- Key Research and Development Program of Shaanxi [2019ZDLSF04-05]
- National Natural Science Foundation of China [81773882, 81974522]
- Subject Innovation Team of Shaanxi University of Chinese Medicine [2019-YL10]
This article reviews the global emergence of new variants of the SARS-CoV-2 virus and provides detailed information on several variants of concern and their characteristics. The article emphasizes the clinical characteristics of these variants and provides up-to-date information on the recent variants. The summarized information can help researchers formulate reasonable strategies to combat the ongoing COVID-19 pandemic.
In addition to the rapid, global spread of SARS-CoV-2, new and comparatively more contagious variants are of considerable concern. These emerging mutations have become a threat to the global public health, creating COVID-19 surges in different countries. However, information on these emerging variants is limited and scattered. In this review, we discuss new variants that have emerged worldwide and identify several variants of concern, such as B.1.1.7, B.1.351, P.1, B.1.617.2 and B.1.1.529, and their basic characteristics. Other significant variants such as C.37, B.1.621, B.1.525, B.1.526, AZ.5, C.1.2, and B.1.617.1 are also discussed. This review highlights the clinical characteristics of these variants, including transmissibility, pathogenicity, susceptible population, and re-infectivity. It provides the latest information on the recent variants of SARS-CoV-2. The summary of this information will help researchers formulate reasonable strategies to curb the ongoing COVID19 pandemic.
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