4.7 Article

Cobalt-catalyzed C(sp3)-H bond functionalization to access indole derivatives

期刊

ORGANIC CHEMISTRY FRONTIERS
卷 9, 期 14, 页码 3723-3729

出版社

ROYAL SOC CHEMISTRY
DOI: 10.1039/d2qo00562j

关键词

-

资金

  1. NSFC [21772179]
  2. Program for Science & Technology Innovation Talents in Universities of Henan Province [19HASTIT038]

向作者/读者索取更多资源

This article describes an efficient method for cobalt-catalyzed C(sp(3))-H bond functionalization to synthesize indole derivatives, achieved through sequential C-H activation. The method offers mild reaction conditions, low cost, and good functional group tolerance.
Herein, we develop an efficient method for cobalt-catalyzed C(sp(3))-H bond functionalization to synthesize indole derivatives. The highlight of this protocol is accomplished by sequential C-H activation. This cobalt/organic oxidant catalysis involves cheap Co(OAc)(2)center dot 4H(2)O and ArSO2NHOR and features mild conditions, low cost, and good functional group tolerance. Substrates containing primary or secondary inert C(sp(3))-H bonds were well applied to this strategy. In addition, the isolated dehydrogenation byproduct indicated that the reaction might involve sequential C-H bond activation.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.7
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据