4.7 Article

A pilot study of micro-CT-based whole tissue imaging (WTI) on endoscopic submucosal dissection (ESD) specimens

期刊

SCIENTIFIC REPORTS
卷 12, 期 1, 页码 -

出版社

NATURE PORTFOLIO
DOI: 10.1038/s41598-022-13907-6

关键词

-

资金

  1. Warren Alpert Foundation
  2. 3DHISTECH Ltd.
  3. Hamamatsu Photonics K.K.
  4. Nikon Metrology NV
  5. National Institutes of Health/ National Cancer Institute [P30CA008748]

向作者/读者索取更多资源

Endoscopic submucosal dissection is an effective method for treating large superficial gastrointestinal lesions. This study successfully generated three-dimensional images of nine samples using a micro-CT imaging system, which can provide valuable information for evaluating the extent of the lesion and surgical margins.
Endoscopic submucosal dissection can remove large superficial gastrointestinal lesions in en bloc. A detailed pathological evaluation of the resected specimen is required to assess the risk of recurrence after treatment. However, the current method of sectioning specimens to a thickness of a few millimeters does not provide information between the sections that are lost during the preparation. In this study, we have produced three-dimensional images of the entire dissected lesion for nine samples by using micro-CT imaging system. Although it was difficult to diagnose histological type on micro-CT images, it successfully evaluates the extent of the lesion and its surgical margins. Micro-CT images can depict sites that cannot be observed by the conventional pathological diagnostic process, suggesting that it may be useful to use in a complementary manner.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.7
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据