4.6 Article

A triphenylphosphine coordinated cinnamaldehyde-derived copper(I) Fenton-like agent with mitochondrial aggregation damage for chemodynamic therapy

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Engineering, Biomedical

Precise magnetic resonance imaging-guided sonodynamic therapy for drug-resistant bacterial deep infection

Dong Wang et al.

Summary: The study introduces a novel approach for treating drug-resistant deep bacterial infections using a polymer-peptide-porphyrin conjugate (PPPC) to achieve accurate and deep sonodynamic therapy (SDT). PPPC can be monitored in real-time at the infectious site and effectively eliminates drug-resistant bacteria, showing promising applications in the field.

BIOMATERIALS (2021)

Article Chemistry, Multidisciplinary

Ferrocene-containing polymersome nanoreactors for synergistically amplified tumor-specific chemodynamic therapy

Yuheng Wang et al.

Summary: By loading GOD and TPZ in responsive polymersome nanoreactors, tumor acidic microenvironment can trigger the release of TPZ prodrugs, leading to the conversion of oxygen and glucose into H2O2 under the catalysis of ferrocene and subsequent generation of (OH)• radicals. This synergistic effect efficiently kills tumor cells and suppresses tumor growth, demonstrating the potential of ferrocene-containing responsive polymersome nanoreactors as a potent nano-platform for amplified CDT.

JOURNAL OF CONTROLLED RELEASE (2021)

Article Chemistry, Multidisciplinary

Double-Lock Nanomedicines Enable Tumor-Microenvironment-Responsive Selective Antitumor Therapy

Fang Liu et al.

Summary: A hybrid nanocarrier is developed to deliver chemotherapy drugs selectively to tumor cells, reducing off-target adverse effects. The two-step unlocking process enables enhanced intracellular uptake of the drug within tumor cells, promising efficacy enhancement and side-effect reduction in chemotherapeutics.

ADVANCED FUNCTIONAL MATERIALS (2021)

Article Chemistry, Multidisciplinary

Pd-Single-Atom Coordinated Biocatalysts for Chem-/Sono-/Photo-Trimodal Tumor Therapies

Fangxue Du et al.

Summary: A novel and facile Pd-single-atom-coordinated porphyrin-based polymeric network for chem-/sono-/photo-trimodal tumor therapies has been designed, showing highly efficient biocatalytic sites and synergistic trimodal therapeutic effects in both in vitro and in vivo experiments.

ADVANCED MATERIALS (2021)

Review Chemistry, Multidisciplinary

Mito-Bomb: Targeting Mitochondria for Cancer Therapy

Xiaolu Guo et al.

Summary: Traditional cancer therapies such as surgery, chemotherapy, and radiotherapy have limited effectiveness, while photodynamic therapy, photothermal therapy, and chemodynamic therapy have shown promising results in cancer treatment due to their high selectivity, minimal resistance, and minimal toxicity.

ADVANCED MATERIALS (2021)

Review Chemistry, Multidisciplinary

Recent advances in enhanced chemodynamic therapy strategies

Qiwei Tian et al.

Summary: Chemodynamic therapy (CDT) is a novel therapeutic modality that aims to destroy cancer cells using Fenton reactions without external energy input. Various strategies have been explored to enhance the efficiency of CDT, including increasing the production, accelerating generation, and enhancing efficacy of hydroxyl radicals.

NANO TODAY (2021)

Article Chemistry, Multidisciplinary

NIR-Activated Multimodal Photothermal/Chemodynamic/Magnetic Resonance Imaging Nanoplatform for Anticancer Therapy by Fe(II) Ions Doped MXenes (Fe-Ti3C2)

Yizhang Wu et al.

Summary: In this study, Fe2+ ions were doped into 2D TC NSs to synthesize a novel FTC nanoshell, which exhibited superior PTCE due to enhanced conductivity through interlaminar ferrous ion-channels. The FTC also showed abilities of ROS releasing and GSH suppression triggered by NIR laser, making it a promising nanoplatform for biomedical applications, including bioimaging and drug loading.
Article Multidisciplinary Sciences

Peroxisome inspired hybrid enzyme nanogels for chemodynamic and photodynamic therapy

Xing Qin et al.

Summary: This study demonstrates a peroxisome-inspired approach for tumor therapy by incorporating lactate oxidase and catalase into nanoparticles. This method effectively inhibits tumor growth by regulating intracellular ROS levels.

NATURE COMMUNICATIONS (2021)

Article Nanoscience & Nanotechnology

Light-Induced Reactive Oxygen Species (ROS) Generator for Tumor Therapy through an ROS Burst in Mitochondria and AKT-Inactivation-Induced Apoptosis

Yinuo Tu et al.

Summary: Mitochondria are a valuable target for cancer therapy due to their function in energy supply and cellular signal regulation. A light-induced ROS generator TBTP has been developed for mitochondria-targeting ROS-associated therapy, showing effective anticancer potential by destroying mitochondria integrity and inducing cell apoptosis, indicating great potential in cancer therapy.

ACS APPLIED BIO MATERIALS (2021)

Article Engineering, Environmental

Intelligent nanoenzyme for T1-weighted MRI guided theranostic applications

Bingqian Guo et al.

CHEMICAL ENGINEERING JOURNAL (2020)

Article Chemistry, Multidisciplinary

Modulating intracellular oxidative stress via engineered nanotherapeutics

Jinming Hu et al.

JOURNAL OF CONTROLLED RELEASE (2020)

Article Nanoscience & Nanotechnology

Integration of Fe3O4 with Bi2S3 for Multi-Modality Tumor Theranostics

Keyi Luo et al.

ACS APPLIED MATERIALS & INTERFACES (2020)

Review Biochemical Research Methods

Metal-Based Nanocatalyst for Combined Cancer Therapeutics

Yu Han et al.

BIOCONJUGATE CHEMISTRY (2020)

Review Oncology

Clinical development and potential of photothermal and photodynamic therapies for cancer

Xingshu Li et al.

NATURE REVIEWS CLINICAL ONCOLOGY (2020)

Review Chemistry, Multidisciplinary

Metal-organic complex-based chemodynamic therapy agents for cancer therapy

Eunbin Hwang et al.

CHEMICAL COMMUNICATIONS (2020)

Review Chemistry, Multidisciplinary

Chemodynamic Therapy: Tumour Microenvironment-Mediated Fenton and Fenton-like Reactions

Zhongmin Tang et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

Article Chemistry, Multidisciplinary

Restraining Cancer Cells by Dual Metabolic Inhibition with a Mitochondrion-Targeted Platinum(II) Complex

Kun Wang et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

Review Oncology

Reactive oxygen species and cancer: A complex interaction

Sankaralingam Saikolappan et al.

CANCER LETTERS (2019)

Article Chemistry, Multidisciplinary

Synthesis of Copper Peroxide Nanodots for H2O2 Self-Supplying Chemodynamic Therapy

Li-Sen Lin et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)

Article Engineering, Biomedical

Energy-Free, Singlet Oxygen-Based Chemodynamic Therapy for Selective Tumor Treatment without Dark Toxicity

Yanrui Chen et al.

ADVANCED HEALTHCARE MATERIALS (2019)

Article Chemistry, Multidisciplinary

Upconversion-mediated ZnFe2O4 nanoplatform for NIR-enhanced chemodynamic and photodynamic therapy

Shuming Dong et al.

CHEMICAL SCIENCE (2019)

Article Chemistry, Multidisciplinary

Simultaneous Fenton-like Ion Delivery and Glutathione Depletion by MnO2-Based Nanoagent to Enhance Chemodynamic Therapy

Li-Sen Lin et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)

Article Multidisciplinary Sciences

Starfish Apaf-1 activates effector caspase-3/9 upon apoptosis of aged eggs

Ritsuko Tamura et al.

SCIENTIFIC REPORTS (2018)

Review Chemistry, Multidisciplinary

Generation and Detection of Reactive Oxygen Species in Photocatalysis

Yoshio Nosaka et al.

CHEMICAL REVIEWS (2017)

Review Chemistry, Multidisciplinary

Promises, facts and challenges for graphene in biomedical applications

Giacomo Reina et al.

CHEMICAL SOCIETY REVIEWS (2017)

Article Chemistry, Multidisciplinary

Synthesis of Iron Nanometallic Glasses and Their Application in Cancer Therapy by a Localized Fenton Reaction

Chen Zhang et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2016)

Article Medicine, Research & Experimental

Mitochondrial calcium uptake underlies ROS generation during aminoglycoside-induced hair cell death

Robert Esterberg et al.

JOURNAL OF CLINICAL INVESTIGATION (2016)

Article Chemistry, Multidisciplinary

Hydrogen Peroxide Displacing DNA from Nanoceria: Mechanism and Detection of Glucose in Serum

Biwu Liu et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2015)

Article Chemistry, Multidisciplinary

SHELXT - Integrated space-group and crystal-structure determination

George M. Sheldrick

ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES (2015)

Article Chemistry, Multidisciplinary

Crystal structure refinement with SHELXL

George M. Sheldrick

ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY (2015)

Article Chemistry, Multidisciplinary

Dual pH-sensitive oxidative stress generating micellar nanoparticles as a novel anticancer therapeutic agent

Sanga Park et al.

JOURNAL OF CONTROLLED RELEASE (2014)

Software Review Chemistry, Multidisciplinary

OLEX2: a complete structure solution, refinement and analysis program

Oleg V. Dolomanov et al.

JOURNAL OF APPLIED CRYSTALLOGRAPHY (2009)

Review Cell Biology

Role of oxygen radicals in DNA damage and cancer incidence

M Valko et al.

MOLECULAR AND CELLULAR BIOCHEMISTRY (2004)