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Stem cells to reverse aging

期刊

CHINESE MEDICAL JOURNAL
卷 135, 期 8, 页码 901-910

出版社

LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/CM9.0000000000001984

关键词

Aging; anti-aging; Stem cells; Exosome

资金

  1. Yunnan Talent Project [2018HB002]
  2. Army Animal Special Project [SYDW[2020]19]

向作者/读者索取更多资源

Addressing the problems associated with global aging has become a current research focus as human life expectancy continues to increase and the birth rate declines. Stem cell therapies have the potential to delay or even reverse aging, but ideal treatments have not been found yet.
As human life expectancy continues to increase and the birth rate continues to decline, the phenomenon of aging is becoming more prominent worldwide. Therefore, addressing the problems associated with global aging has become a current research focus. The main manifestations of human aging are structural degeneration and functional decline of aging tissues and organs, quality of life decline, decreased ability to resist diseases, and high incidence rates of a variety of senile degenerative diseases. Thus far, no ideal treatments have been found. Stem cell (SC) therapies have broad application prospects in the field of regenerative medicine due to the inherent biological characteristics of SCs, such as their plasticity, self-renewal, and multidirectional differentiation potential. Thus, SCs could delay or even reverse aging. This manuscript reviews the causes of human aging, the biological characteristics of SCs, and research progress on age reversal.

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