4.7 Review

Nanoparticle-Containing Wound Dressing: Antimicrobial and Healing Effects

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Toxicology

Effect of nano zinc oxide on proliferation and toxicity of human gingival cells

Fang-Chuan Chen et al.

Summary: This study explored the toxicity of ZnO nanoparticles (ZnO NPs) to human gingival fibroblast cells (HGF-1) and its effect on cell proliferation. The results showed that high concentrations of ZnO NPs inhibited cell proliferation, disrupted cell membrane integrity, and induced oxidative stress and apoptosis. Additionally, high concentrations of ZnO NPs also inhibited HGF-1 proliferation by regulating the expression of MDM2 and p53.

HUMAN & EXPERIMENTAL TOXICOLOGY (2022)

Article Biochemistry & Molecular Biology

Novel design of bandages using cotton pads, doped with chitosan, glycogen and ZnO nanoparticles, having enhanced antimicrobial and wounds healing effects

Mohamed Hasanin et al.

Summary: This study presents a new design for antimicrobial wound bandages, which use cotton fibers reinforced with elastic compression straps and incorporate a wound healing biocomposite. The dressings showed a faster and more complete healing process compared to control groups, and also exhibited significant antimicrobial activity against pathogenic microorganisms commonly found in wounds.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2022)

Review Biochemistry & Molecular Biology

Nano-silver functionalized polysaccharides as a platform for wound dressings: A review

Yucheng Yuan et al.

Summary: Healing of defective skin tissue, especially chronic wounds, is a complex process that can cause extensive suffering and high cost for patients. Traditional wound dressings are not sufficient for the whole wound healing process, so there is a need to develop new wound dressings with multiple functions. Nano-silver and naturally derived polysaccharides have shown great potential in wound healing due to their antibacterial properties, good biocompatibility, and affordability.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2022)

Article Polymer Science

Chitosan coated metallic nanoparticles with stability, antioxidant, and antibacterial properties: Potential for wound healing application

Maryam Sharifiaghdam et al.

Summary: Metal nanoparticles have been widely used in wound treatment due to their antibacterial activity and wound healing effects. This study demonstrates the synthesis and application potential of copper, silver, gold, and selenium nanoparticles in terms of stability, antibacterial and antioxidant effects, and cellular interactions. Gold and selenium nanoparticles show high stability, antioxidant efficacy, and antibacterial effects, with potential as effective antibiotics.

JOURNAL OF APPLIED POLYMER SCIENCE (2022)

Article Chemistry, Physical

Biodegradable gelatin/silver nanoparticle composite cryogel with excellent antibacterial and antibiofilm activity and hemostasis for Pseudomonas aeruginosa-infected burn wound healing

Ying Huang et al.

Summary: GT/Ag cryogels with outstanding antibacterial properties and effective absorption of wound exudates are excellent candidates for promoting burn wound repair.

JOURNAL OF COLLOID AND INTERFACE SCIENCE (2022)

Article Chemistry, Multidisciplinary

Using artificial neural network for design and development of PVA/chitosan/starch/heparinized nZnO hydrogels for enhanced wound healing

Alireza Joorabloo et al.

Summary: A study employed response surface methodology and artificial neural network to design hydrogel dressings including polyvinyl alcohol, chitosan, and starch. The addition of zinc-oxide nanoparticles and heparin improved the physical and mechanical properties, antibacterial activities, and wound healing ability of the hydrogel dressings.

JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY (2022)

Article Polymer Science

Cellulose-Based Hybrid Nanoarchitectonics with Silver Nanoparticles: Characterization and Antimicrobial Potency

E. S. Madivoli et al.

Summary: This study demonstrates that 2,2,6,6-Tetramethylpiperidin-1-yl oxyl (TEMPO) oxidized cellulose nanofibrils (CNFs) decorated with silver nanoparticles (AgNPs) can inhibit the growth of microorganisms. The nanocomposite exhibits higher thermal stability and fiber length, making it a potential candidate for antimicrobial wound dressings.

JOURNAL OF INORGANIC AND ORGANOMETALLIC POLYMERS AND MATERIALS (2022)

Article Polymer Science

Mechanical and antibacterial properties of ZnO/chitosan bio-composite films

Ayse Kalemtas et al.

Summary: The study showed that the concentration and particle size of ZnO powders significantly affected the mechanical and antibacterial properties of ZnO/chitosan bio-composite films. Bio-composite films with high ZnO content demonstrated good antibacterial activities against various bacteria, making them promising materials for applications like food packaging and antibacterial coatings.

JOURNAL OF POLYMER ENGINEERING (2022)

Article Chemistry, Applied

Silver/poly(vinyl alcohol)/graphene hydrogels for wound dressing applications: Understanding the mechanism of silver, antibacterial agent release

Katarina Nesovic et al.

Summary: This study aimed to analyze silver release from electrochemically synthesized antibacterial silver nanoparticles loaded poly(vinyl alcohol) hydrogels for wound dressing applications, showing potential in antibacterial activity assessment against Staphylococcus aureus and Escherichia coli bacterial strains.

JOURNAL OF VINYL & ADDITIVE TECHNOLOGY (2022)

Article Materials Science, Multidisciplinary

Injectable nanocomposite hydrogel as wound dressing agent with tunable multifunctional property

Kummara Madhusudana Rao et al.

Summary: The injectable nanocomposite hydrogel developed in this study has tunable multifunctional properties such as cell adhesive, antibacterial, and hemostatic effects, making it a potential wound dressing agent.

MATERIALS LETTERS (2022)

Article Chemistry, Multidisciplinary

The construction of a seaweed-based antibacterial membrane loaded with nano-silver based on the formation of a dynamic united dual network structure

Ming Yan et al.

Summary: By loading silver nanoparticles into a CA-PDA-CMCS membrane, a hydrogel membrane with excellent mechanical and antibacterial properties, Ag@CA-PDA-CMCS membrane was prepared. It showed obvious antibacterial effects against Escherichia coli and Staphylococcus aureus and has great potential for use in new wound dressings.

NEW JOURNAL OF CHEMISTRY (2022)

Article Chemistry, Inorganic & Nuclear

An overview on biomedical applications of versatile silica nanoparticles, synthesized via several chemical and biological routes: A review

Shagun Varshney et al.

Summary: Silica nanoparticles have attracted global attention due to their excellent biological, mechanical, and physiochemical properties. This review article discusses different synthetic routes, reagents, characterization techniques, and applications of silica nanoparticles, highlighting their potential in biomedical applications.

PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS (2022)

Article Materials Science, Characterization & Testing

Preparation and application of poly (hydroxyl ethyl methacrylate) nanocomposite hydrogels containing iron oxide nanoparticles as wound dressing

Azin Paydayesh et al.

Summary: This study reports the preparation and application of pHEMA nanocomposite hydrogels containing iron oxide nanoparticles as wound dressings. The nanocomposite hydrogels exhibited good mechanical properties, suitable water vapor transmission rate and porosity, and higher cell survival rate and antibacterial properties compared to pure pHEMA.

POLYMERS & POLYMER COMPOSITES (2022)

Review Nanoscience & Nanotechnology

Conductive Biomaterials as Bioactive Wound Dressing for Wound Healing and Skin Tissue Engineering

Rui Yu et al.

Summary: This review summarizes the design and application of conductive biomaterials for wound healing and skin tissue engineering. Conductive biomaterials with various structural forms, such as films, nanofibers, membranes, hydrogels, sponges, foams, and acellular dermal matrix, play important roles in electrotherapy, wound dressing, and wound assessment, and possess promising applications in the field.

NANO-MICRO LETTERS (2022)

Article Polymer Science

In Situ Growth of Silver Nanoparticles on Chitosan Matrix for the Synthesis of Hybrid Electrospun Fibers: Analysis of Microstructural and Mechanical Properties

Karina Santiago-Castillo et al.

Summary: This study reports a two-step process for the preparation of PVA-CTS-Ag electrospun fibers and analyzes their microstructural, mechanical, and antibacterial properties, confirming their potential application in the biomedical field.

POLYMERS (2022)

Article Polymer Science

Fabrication of Nanofibers Based on Hydroxypropyl Starch/Polyurethane Loaded with the Biosynthesized Silver Nanoparticles for the Treatment of Pathogenic Microbes in Wounds

Mohamed E. El-Hefnawy et al.

Summary: The fabrication of electrospun nanofibers blended with modified natural polymer and synthetic polymers offers great potential for biomedical applications. The addition of biosynthesized silver nanoparticles, prepared using extract from Nerium oleander leaves, enhances the antimicrobial properties of the nanofibers. The results showed that the presence of hydroxyl propyl starch (HPS) decreased the contact angle and increased the hydrophilicity of the nanofibers, while the addition of silver nanoparticles exhibited incredible antimicrobial activity against pathogenic microbes.

POLYMERS (2022)

Article Polymer Science

Polymeric Dental Nanomaterials: Antimicrobial Action

Pavel Yudaev et al.

Summary: This review summarizes and critically analyzes studies on the application of polymeric dental nanomaterials as antimicrobial materials in various fields of dentistry published in the past four years. The review identifies promising nanomaterials for dental therapy and endodontics, orthodontics, periodontics, dental implantology, dental prosthetics, therapeutic dentistry, and maxillofacial surgery. The analysis reveals that composites based on silver nanoparticles, zinc(II), titanium(IV), magnesium(II), and copper(II) oxide nanoparticles, chitosan nanoparticles, calcium phosphate or fluoride nanoparticles, and nanodiamonds have shown potential for use in dental applications, while composites based on hydroxyapatite and bioactive glass nanoparticles have proven to be less efficient.

POLYMERS (2022)

Article Materials Science, Biomaterials

PLLA-gelatin composite fiber membranes incorporated with functionalized CeNPs as a sustainable wound dressing substitute promoting skin regeneration and scar remodeling

Yarong Lv et al.

Summary: In this study, cerium oxide nanoparticle incorporated PLLA-gelatin composite fiber membranes were fabricated for wound healing applications. The membranes showed good morphology, water absorption, and improved mechanical properties. In vitro and in vivo experiments confirmed their efficacy in promoting cell proliferation and wound recombination.

JOURNAL OF MATERIALS CHEMISTRY B (2022)

Article Chemistry, Multidisciplinary

Biocompatible and Antimicrobial Cellulose Acetate-Collagen Films Containing MWCNTs Decorated with TiO2 Nanoparticles for Potential Biomedical Applications

Madalina Elena David et al.

Summary: This study focuses on the synthesis of TiO2-decorated multi-walled carbon nanotubes and their incorporation into cellulose acetate-collagen films to obtain a new biomaterial with potential biomedical applications and improved antimicrobial activity. The results show that the presence of the nanocomposites enhances and maintains the antimicrobial activity of the wound dressings, and the obtained films exhibit good biocompatibility.

NANOMATERIALS (2022)

Article Energy & Fuels

Biopolymer starch-gelatin embedded with silver nanoparticle-based hydrogel composites for antibacterial application

Sapna Sethi et al.

Summary: A multi-component starch-gelatin hybrid hydrogel was synthesized using an eco-friendly approach. The addition of gelatin enhanced the mechanical strength of the hybrid hydrogel, and the embedded silver nanoparticles provided antimicrobial activity. This silver-embedded starch-gelatin hydrogel exhibited good physical and chemical properties, making it suitable for wound dressing materials.

BIOMASS CONVERSION AND BIOREFINERY (2022)

Article Multidisciplinary Sciences

Polyvinyl alcohol/corn starch/castor oil hydrogel films, loaded with silver nanoparticles biosynthesized in Mentha piperita leaves' extract

Mariam Mojally et al.

Summary: Hydrogel films were prepared from silver nanoparticles (SNP) synthesized with plant extracts, along with other constituents. The films were flexible, biodegradable, exhibited antibacterial properties, and showed high thermal stability, making them suitable for wound dressings.

JOURNAL OF KING SAUD UNIVERSITY SCIENCE (2022)

Review Biochemistry & Molecular Biology

Composite Membrane Dressings System with Metallic Nanoparticles as an Antibacterial Factor in Wound Healing

Angelika Kwiatkowska et al.

Summary: This review paper discusses the application of nanomaterials in wound dressings, particularly metallic nanoparticles, and their use as antimicrobial factors. The paper also explores the multiple molecular pathways, cell types, and agents involved in wound healing, as well as the categorization of wound dressings and the materials and membrane constructs used in them. Furthermore, the paper examines the role of bacteria in wound healing and the antibacterial mechanism of nanoparticles. Overall, the review provides valuable insights into the potential of nanocomposite materials in improving wound healing processes.

MEMBRANES (2022)

Article Polymer Science

Production and characterization of hybrid nanofiber wound dressing containing Centella asiatica coated silver nanoparticles by mutual electrospinning method

Ogun Bozkaya et al.

Summary: The aim of this study was to develop a therapeutic and antimicrobial nanofiber wound dressing material with suitable physical properties. This was achieved by synthesizing Centella asiatica coated silver nanoparticles and electrospinning them with poly caprolactone and polyethylene oxide to produce hybrid nanofibers. The surface and physico-chemical properties were characterized, and the degradation and antimicrobial properties were investigated. The results demonstrated the potential of this material for wound healing applications.

EUROPEAN POLYMER JOURNAL (2022)

Article Chemistry, Inorganic & Nuclear

An Effective Wound Healing Material Based on Gold Incorporation into a Heparin-Polyvinyl Alcohol Nanocomposite: Enhanced In Vitro and In Vivo Care of Perioperative Period

Kunxian Zhang et al.

Summary: The study fabricated a highly porous H-PVA@Au nanocomposite dressing with good antimicrobial activity and biocompatibility, suitable for treating burn injuries.

JOURNAL OF CLUSTER SCIENCE (2022)

Article Biochemistry & Molecular Biology

Quaternized chitin/tannic acid bilayers layer-by-layer deposited poly(lactic acid)/polyurethane nanofibrous mats decorated with photoresponsive complex and silver nanoparticles for antibacterial activity

Aying Zhou et al.

Summary: This study successfully constructed a novel hybrid nanofiber using electrospinning technology, which can be used as a multifunctional antibacterial dressing for chronic wounds. The material exhibits excellent flexibility, antibacterial activity, hemocompatibility, and ROS scavenging ability, and promotes wound healing.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2022)

Article Biochemistry & Molecular Biology

Development and Characterization of Highly Stable Silver NanoParticles as Novel Potential Antimicrobial Agents for Wound Healing Hydrogels

Alessio Massironi et al.

Summary: Recurrent microbial infections are a major cause of surgical failure and morbidity. Wound healing strategies based on hydrogels, which provide a barrier against pathogen microbial colonization and a favorable environment for tissue repair, have been proposed. However, most hydrogel materials have bacteriostatic rather than antimicrobial properties and lack specific action against pathogens. In this study, highly stable silver nanoparticles (AgNPs) were developed as potential antimicrobial agents for hyaluronic acid hydrogels. Two stabilizing agents obtained from natural and renewable sources, cellulose nanocrystals and ulvan polysaccharide, were used to ensure the stability of the silver colloid. The developed AgNPs showed high stability and strong antimicrobial activity when loaded into photocrosslinked methacrylated hyaluronic acid hydrogels.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

Article Materials Science, Multidisciplinary

Additive manufacturing of antibacterial PLA-ZnO nanocomposites: Benefits, limitations and open challenges

Wei Juene Chong et al.

Summary: This review introduces PLA-ZnO nanocomposites and analyzes the main factors influencing their antibacterial activity. The importance of embedded antibacterial functions in applications such as food packaging and wound dressing is discussed. The emerging research on the additive manufacturing of PLA-ZnO nanocomposites, particularly in fused filament fabrication, is highlighted, along with the associated challenges.

JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY (2022)

Article Chemistry, Inorganic & Nuclear

Synthesis of antibiotic-modified silica nanoparticles and their use as a controlled drug release system with antibacterial properties

Betul Yilmaz et al.

Summary: In this study, monodispersed silica nanoparticles were synthesized and modified to achieve drug release and antibacterial properties. The modified nanoparticles exhibited controlled drug release behavior and showed antibacterial activity against various bacteria.

PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS (2022)

Article Polymer Science

pH-Responsive Nanocarriers in Cancer Therapy

Nour M. AlSawaftah et al.

Summary: Stimuli-responsive nanoparticles have shown promising potential in overcoming the limitations of conventional chemotherapy. pH-sensitive nanoparticles, in particular, have proven to be highly efficient in delivering drugs to tumors compared to conventional nanoparticles. This review summarizes the different strategies used to develop pH-sensitive nanoparticles for cancer therapy.

POLYMERS (2022)

Article Polymer Science

Evaluation of the Performance of a ZnO-Nanoparticle-Coated Hydrocolloid Patch in Wound Healing

Van Anh Thi Le et al.

Summary: Hydrocolloid dressings combined with zinc oxide nanoparticles were found to accelerate wound healing rates, reduce inflammation, and promote the proliferation phase of the healing process. This cost-effective and UV-blocking treatment showed significant improvements in both in vivo and in vitro models, providing a promising approach for wound dressing.

POLYMERS (2022)

Article Materials Science, Multidisciplinary

Novel multifunctional dual-dynamic-bonds crosslinked hydrogels for multi-strategy therapy of MRSA-infected wounds

Pengpeng Deng et al.

Summary: This study developed a novel multifunctional hydrogel for wound healing by utilizing the electrostatic interaction between phenylboric acid and chitosan, as well as the dynamic borate ester bond formed between phenylboric acid and PDA-modified CNTs. The hydrogel exhibited fast self-healing properties, excellent adhesion strength, as well as advantages such as injectability, shape adaptation, antioxidant properties, biocompatibility, blood compatibility, electrical conductivity, and photothermal antibacterial properties. In an MRSA-infected wound model, the hydrogel effectively reduced inflammation, promoted collagen deposition, epithelial tissue and vascular regeneration, and accelerated wound healing. This work provides a new approach for multi-strategy therapy in wound healing with promising clinical applications.

APPLIED MATERIALS TODAY (2022)

Article Materials Science, Multidisciplinary

Diversified antibacterial modification and latest applications of polysaccharide-based hydrogels for wound healthcare

Rong Zhang et al.

Summary: This article reviews the antibacterial modes, mechanisms, and modification methods of natural polysaccharide hydrogels as wound dressings. It is found that polysaccharide-based antibacterial hydrogels can form sterilized micro-spaces in wounds, accelerate wound healing, and prevent bacterial invasion and accumulation. However, there are still some problems in the application of natural polysaccharide antibacterial hydrogels.

APPLIED MATERIALS TODAY (2022)

Article Materials Science, Multidisciplinary

Electrospinning polyacrylonitrile (PAN) based nanofiberous membranes synergic with plant antibacterial agent and silver nanoparticles (AgNPs) for potential wound dressing

Pinhong Chen et al.

Summary: Nanofiberous membranes incorporated with curcumin, tannic acid and silver nanoparticles were successfully fabricated by electrospinning. Characterization and analysis showed that the obtained composite membranes had good physicochemical properties and biocompatibility, making them suitable for wound prevention against free radicals and bacteria.

MATERIALS TODAY COMMUNICATIONS (2022)

Review Emergency Medicine

Role of copper nanoparticles in wound healing for chronic wounds: literature review

Jessica Salvo et al.

Summary: This review aims to explore the importance of copper nanoparticles in wound healing. Copper nanoparticles combat infection through multiple mechanisms and play a significant role in various stages of wound healing by modulating cytokines and growth factors.

BURNS & TRAUMA (2022)

Article Biotechnology & Applied Microbiology

Antibacterial effect of cerium oxide nanoparticle against Pseudomonas aeruginosa

Khosro Zamani et al.

Summary: This study demonstrated the antimicrobial activity of cerium oxide nanoparticles and gelatin-polycaprolactone nanofibers containing these nanoparticles against Pseudomonas aeruginosa, showing potential for medical applications in wound dressings. The nanoparticles were effective in inhibiting bacterial growth and reducing the expression of resistance genes, indicating their promising role as alternative antibacterial agents.

BMC BIOTECHNOLOGY (2021)

Article Nanoscience & Nanotechnology

Antimicrobial Double-Layer Wound Dressing Based on Chitosan/Polyvinyl Alcohol/Copper: In vitro and in vivo Assessment

Ensieh Ghasemian Lemraski et al.

Summary: This study successfully prepared chitosan/polyvinyl alcohol/copper nanofibers by incorporating copper nanoparticles into nanofiber dressings, demonstrating their effective antimicrobial properties. The prepared hydrogel formulations were shown to provide proper care for open wounds in the early stages of wound healing and prevent the occurrence of prolonged open wounds.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2021)

Article Biochemistry & Molecular Biology

Preparation and characterization of succinyl chitosan and succinyl chitosan nanoparticle film: In vitro and in vivo evaluation of wound healing activity

N. T. Thu Thao et al.

Summary: Novel N-SuC NPs films with antimicrobial and wound healing properties were successfully synthesized and tested, demonstrating excellent efficacy in both in vitro and in vivo studies.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021)

Review Physics, Multidisciplinary

A Mini Review of Antibacterial Properties of ZnO Nanoparticles

Sergey V. Gudkov et al.

Summary: The development of antibiotic resistance in bacteria is a major concern in global healthcare. Zinc oxide nanoparticles have shown high antibacterial potential against both gram-positive and gram-negative bacteria. Studies have explored the influence of nanoparticle size, synthesis methods, and modifications on enhancing antibacterial efficiency.

FRONTIERS IN PHYSICS (2021)

Article Polymer Science

Synergistic Effect of Glycyrrhizic Acid and ZnO/Palygorskite on Improving Chitosan-Based Films and Their Potential Application in Wound Healing

Qian Zhang et al.

Summary: This study prepared nanocomposite films using chitosan, glycyrrhizic acid, and ZnO/palygorskite, which demonstrated good mechanical properties and broad-spectrum antibacterial activity, particularly effective against drug-resistant bacteria. The findings suggest that these films have potential as wound-care materials with enhanced properties.

POLYMERS (2021)

Article Materials Science, Multidisciplinary

Synthesis of environmentally benign antimicrobial dressing nanofibers based on polycaprolactone blended with gold nanoparticles and spearmint oil nanoemulsion

Mehrez E. El-Naggar et al.

Summary: In this study, highly efficient antimicrobial wound dressings were obtained by blending PCL with AuNPs and SNE using the electrospinning method. Characterization of the nanofibers revealed that blending PCL with AuNPs resulted in smooth surface fibers, while the addition of SNE led to a rough surface, indicating good antimicrobial properties in the developed nanofibers.

JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T (2021)

Article Infectious Diseases

Collagen Hydrogels Loaded with Silver Nanoparticles and Cannabis Sativa Oil

Pablo Edmundo Antezana et al.

Summary: This study describes the development of a novel biomaterial - collagen hydrogels loaded with silver nanoparticles and cannabis sativa oil extract, which exhibits long-lasting antimicrobial effects, improved mechanical properties, and enhanced biocompatibility. The results suggest that this nanocomposite biomaterial is a promising alternative for the treatment of wound infections and wound healing.

ANTIBIOTICS-BASEL (2021)

Article Infectious Diseases

Antimicrobial and Wound Healing Properties of FeO Fabricated Chitosan/PVA Nanocomposite Sponge

Anbazhagan Sathiyaseelan et al.

Summary: A new nanocomposite scaffold was developed for accelerated healing of anemia-associated diabetic wounds, showing excellent biological activity and antibacterial properties. The PD-FeO NPs (0.01%) incorporated CS/PVA sponge exhibited promising cell proliferation in vitro wound-healing assay and could be a recommended option for diabetic wound dressing.

ANTIBIOTICS-BASEL (2021)

Article Materials Science, Multidisciplinary

Copper oxide nanoparticles infused electrospun polycaprolactone/gelatin scaffold as an antibacterial wound dressing

Sathish Kumar Karuppannan et al.

Summary: The study focuses on the green synthesis and characterization of copper oxide nanoparticles infused Polycaprolactone/Gelatin electro-spun nanofibers, which show good antimicrobial properties and promote wound healing. The fabricated nanofibers have good performance and can be effectively used in wound care management.

MATERIALS LETTERS (2021)

Article Chemistry, Multidisciplinary

Structure and cytotoxicity of biodegradable poly(D,l-lactide-co-glycolide) nanoparticles loaded with oxaliplatin

Ekaterina Razuvaeva et al.

Summary: Spherical nanoparticles loaded with oxaliplatin were produced by nanoprecipitation using the biocompatible and biodegradable poly(D,l-lactide-co-glycolide) copolymer. The nanoformulation of oxaliplatin demonstrated enhanced cytotoxicity and selectivity against several cancer cells in vitro compared to the free drug.

MENDELEEV COMMUNICATIONS (2021)

Article Biochemistry & Molecular Biology

Preparation and Application of Quaternized Chitosan- and AgNPs-Base Synergistic Antibacterial Hydrogel for Burn Wound Healing

Xushan Chen et al.

Summary: Infection is a major cause of death from burns, and traditional dressings are ineffective at inhibiting bacterial growth; a new hydrogel design shows excellent antibacterial activity and fast wound healing, promising to be a significant advancement in wound dressings.

MOLECULES (2021)

Article Chemistry, Physical

Antimicrobial PAA/PAH Electrospun Fiber Containing Green Synthesized Zinc Oxide Nanoparticles for Wound Healing

Marina Bandeira et al.

Summary: This study introduces a novel antimicrobial material using green synthesized zinc oxide nanoparticles (ZnONPs) incorporated in polymeric fibers for wound healing purposes. The material demonstrated high antimicrobial activity against both Staphylococcus aureus and Escherichia coli, showing potential for wound healing treatments. This composite material mimics the extracellular matrix morphology of skin tissue, indicating promising applications in wound healing.

MATERIALS (2021)

Article Polymer Science

Synthesis of Novel Dental Nanocomposite Resins by Incorporating Polymerizable, Quaternary Ammonium Silane-Modified Silica Nanoparticles

Alexandros K. Nikolaidis et al.

Summary: Various approaches to strengthening dental composite resins with quaternary ammonium compounds have been reported, and this study focuses on investigating the physicochemical and mechanical performance of dental resins containing novel QAC and silica nanofillers. The synthesized QASiC were surface modified onto silica nanoparticles and incorporated into methacrylate based dental resins, leading to improved mechanical properties of the composites. This research provides insights into designing multifunctional dental materials to address challenges in clinical practice.

POLYMERS (2021)

Review Pharmacology & Pharmacy

Electrospun Nanofibers/Nanofibrous Scaffolds Loaded with Silver Nanoparticles as Effective Antibacterial Wound Dressing Materials

Sibusiso Alven et al.

Summary: Nanofibrous scaffolds loaded with silver nanoparticles show promising biological and mechanical outcomes in wound healing, with good antibacterial and bioactive properties.

PHARMACEUTICS (2021)

Article Materials Science, Biomaterials

Cerium Oxide Nanoparticle Incorporated Electrospun Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) Membranes for Diabetic Wound Healing Applications

Robin Augustine et al.

ACS BIOMATERIALS SCIENCE & ENGINEERING (2020)

Article Biochemistry & Molecular Biology

Semi-interpenetrating nanosilver doped polysaccharide hydrogel scaffolds for cutaneous wound healing

G. U. Preethi et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

Article Biochemistry & Molecular Biology

Sprayed in-situ synthesis of polyvinyl alcohol/chitosan loaded silver nanocomposite hydrogel for improved antibacterial effects

Arun Kumar et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

Article Materials Science, Composites

Preparation and characterization of collagen/chitosan composites with silver nanoparticles

Alina Sionkowska et al.

POLYMER COMPOSITES (2020)

Article Cell & Tissue Engineering

Evaluation of keratin biomaterial containing silver nanoparticles as a potential wound dressing in full-thickness skin wound model in diabetic mice

Marek Konop et al.

JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE (2020)

Article Chemistry, Multidisciplinary

Silver Nanoparticles-Composing Alginate/Gelatine Hydrogel Improves Wound Healing In Vivo

Flavia Resende Diniz et al.

NANOMATERIALS (2020)

Article Biochemistry & Molecular Biology

Controlled release of silver ions from AgNPs using a hydrogel based on konjac glucomannan and chitosan for infected wounds

Yungang Jiang et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

Article Materials Science, Biomaterials

Polymer-based wafers containing in situ synthesized gold nanoparticles as a potential wound-dressing material

Karine Modolon Zepon et al.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2020)

Article Materials Science, Biomaterials

Characterization and biological evaluation of a novel silver nanoparticle-loaded collagen-chitosan dressing

Rongfu Li et al.

REGENERATIVE BIOMATERIALS (2020)

Article Biochemistry & Molecular Biology

Chitosan/polypropylene glycol hydrogel composite film designed with TiO2 nanoparticles: A promising scaffold of biomedical applications

Ahmet Ulu et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

Article Materials Science, Biomaterials

A self-adapting hydrogel based on chitosan/oxidized konjac glucomannan/AgNPs for repairing irregular wounds

Yixin Wang et al.

BIOMATERIALS SCIENCE (2020)

Review Toxicology

Potential risks and benefits of zinc oxide nanoparticles: a systematic review

S. Keerthana et al.

CRITICAL REVIEWS IN TOXICOLOGY (2020)

Article Chemistry, Multidisciplinary

Wound dressing change facilitated by spraying zinc ions

Tian Xie et al.

MATERIALS HORIZONS (2020)

Article Ophthalmology

Toxicity assessment of six titanium dioxide nanoparticles in human epidermal keratinocytes

Leshuai W. Zhang et al.

CUTANEOUS AND OCULAR TOXICOLOGY (2019)

Article Chemistry, Physical

Fabrication of antibacterial polyvinylalcohol nanocomposite mats with soluble starch coated silver nanoparticles

Aysen Akturk et al.

COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS (2019)

Review Biochemistry & Molecular Biology

Recent advancements in biopolymer and metal nanoparticle-based materials in diabetic wound healing management

Veena Vijayakumar et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2019)

Article Engineering, Biomedical

In vitro and in vivo evaluation of new PRP antibacterial moisturizing dressings for infectious wound repair

Qianxin Wang et al.

JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION (2019)

Article Chemistry, Physical

Smart release of antimicrobial ZnO nanoplates from a pH-responsive keratin hydrogel

Maria E. Villanueva et al.

JOURNAL OF COLLOID AND INTERFACE SCIENCE (2019)

Article Nanoscience & Nanotechnology

Oleic Acid Double Coated Fe3O4 Nanoparticles as Anti-Melanoma Compounds with a Complex Mechanism of Activity-In Vitro and In Ovo Assessment

Elena-Alina Moaca et al.

JOURNAL OF BIOMEDICAL NANOTECHNOLOGY (2019)

Article Chemistry, Multidisciplinary

In-Vitro Cytotoxicity and Oxidative Stress Induced by Cerium Aminoclay and Cerium Oxide Nanoparticles in Human Skin Keratinocyte Cells

Le Thi Nhu Ngoc et al.

JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY (2019)

Article Biochemistry & Molecular Biology

Copper nanoparticles promote rapid wound healing in acute full thickness defect via acceleration of skin cell migration, proliferation, and neovascularization

Sanaz Alizadeh et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2019)

Article Pharmacology & Pharmacy

Silver nanoparticle impregnated chitosan-PEG hydrogel enhances wound healing in diabetes induced rabbits

Nosheen Masood et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2019)

Article Polymer Science

Characterization of Polyvinyl Alcohol/ZnO Nanocomposite Hydrogels for Wound Dressings

Alireza Khalilipour et al.

JOURNAL OF MACROMOLECULAR SCIENCE PART B-PHYSICS (2019)

Article Materials Science, Biomaterials

Fabrication and in vitro behavior of dual-function chitosan/silver nanocomposites for potential wound dressing applications

A. Hernandez-Rangel et al.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2019)

Article Biotechnology & Applied Microbiology

Copper oxide (CuO) loaded polyacrylonitrile (PAN) nanofiber membranes for antimicrobial breath mask applications

Motahira Hashmi et al.

CURRENT RESEARCH IN BIOTECHNOLOGY (2019)

Article Materials Science, Composites

Composite based on poly(acrylic acid-co-itaconic acid) hydrogel with antibacterial performance

Juan Carlos Carrillo-Rodriguez et al.

POLYMER COMPOSITES (2018)

Article Chemistry, Inorganic & Nuclear

Co-assembled ZnO (shell) - CuO (core) nano-oxide materials for microbial protection

Kokkarachedu Varaprasad

PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS (2018)

Article Materials Science, Textiles

Preparation and Properties of Nylon 4/6 Copolymer Nanofibers Containing Silver-Zeolite Nanoparticles

Hoon Han et al.

FIBERS AND POLYMERS (2018)

Article Nanoscience & Nanotechnology

Characterisation and investigation of antibacterial properties of nylon 66/TPS/Ag NPs nanofibre membranes

Alireza Allafchian et al.

MICRO & NANO LETTERS (2018)

Article Chemistry, Multidisciplinary

ZnO nanoparticle-embedded silk fibroin-polyvinyl alcohol composite film: a potential dressing material for infected wounds

Priyanka P. Patil et al.

NEW JOURNAL OF CHEMISTRY (2018)

Proceedings Paper Materials Science, Multidisciplinary

In vitro Biocompatibility and Antibacterial Activity of Gamma Ray Crosslinked ZnO/PVA Hydrogel Nanocomposites

K. Swaroop et al.

MATERIALS TODAY-PROCEEDINGS (2018)

Article Chemistry, Multidisciplinary

Effects of titanium dioxide nanoparticles on human keratinocytes

Clayton Wright et al.

DRUG AND CHEMICAL TOXICOLOGY (2017)

Review Biochemistry & Molecular Biology

Chitosan: A potential biopolymer for wound management

Ijaz Bano et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2017)

Review Nanoscience & Nanotechnology

The antimicrobial activity of nanoparticles: present situation and prospects for the future

Linlin Wang et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2017)

Article Pharmacology & Pharmacy

Comparison of silver nanoparticles stored under air or argon with respect to the induction of intracellular free radicals and toxic effects toward keratinocytes

Sebastian Ahlberg et al.

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2014)

Article Pharmacology & Pharmacy

Cytotoxicity and Genotoxicity of Copper Oxide Nanoparticles in Human Skin Keratinocytes Cells

Saud Alarifi et al.

INTERNATIONAL JOURNAL OF TOXICOLOGY (2013)

Article Medicine, General & Internal

Safety of Chitosan Bandages in Shellfish Allergic Patients

Kirk H. Waibel et al.

MILITARY MEDICINE (2011)

Article Toxicology

DNA damaging potential of zinc oxide nanoparticles in human epidermal cells

Vyom Sharma et al.

TOXICOLOGY LETTERS (2009)