4.8 Article

Guidelines for measuring reactive oxygen species and oxidative damage in cells and in vivo

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

Mitochondrial superoxide targets energy metabolism to modulate epigenetic regulation of NRF2-mediated transcription

Sanjit K. Dhar et al.

Summary: This study reveals the regulatory role of mitochondrial-generated superoxide radicals in gene expression and establishes a new paradigm that recognizes O2· as an initiator of metabolic reprogramming and epigenetic regulation in response to mitochondrial dysfunction.

FREE RADICAL BIOLOGY AND MEDICINE (2022)

Article Cell Biology

Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology

Helmut Sies et al.

Summary: This article discusses the key issues associated with identifying the physiological roles of oxidants, with a focus on H2O2 and O-2(.-). The article emphasizes the need for more precise measurement of oxidants and specific identification of their signaling targets. It also highlights the importance of inter-organellar communication and the contribution of environmental exposures. Development of tools for real-time detection and quantification of individual oxidants is crucial for achieving these goals.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2022)

Article Multidisciplinary Sciences

Hypocrates is a genetically encoded fluorescent biosensor for (pseudo)hypohalous acids and their derivatives

Alexander I. Kostyuk et al.

Summary: In this study, we developed a fluorescent genetically encoded biosensor, Hypocrates, for the visualization of (pseudo) hypohalous acids and their derivatives. Hypocrates is ratiometric, reversible, and highly sensitive. By solving its X-ray structure, we revealed its sensing mechanism and successfully applied it in bacterial stress imaging and a zebrafish tail fin injury model.

NATURE COMMUNICATIONS (2022)

Article Biochemistry & Molecular Biology

Cyclic Hydroxylamines as Monitors of Peroxynitrite and Superoxide-Revisited

Uri Samuni et al.

Summary: The study found that cyclic hydroxylamines cannot react directly with peroxynitrite, but they can be oxidized to their respective nitroxide radicals by the radicals formed during peroxynitrite self-decomposition. However, the yield of accumulated nitroxides is much lower than expected due to competing reactions with other radicals. Therefore, cyclic hydroxylamines cannot be used for quantitative assay of peroxynitrite in vitro, but certain 5-membered ring hydroxylamines can be considered as stoichiometric monitors of superoxide.

ANTIOXIDANTS (2022)

Review Biochemistry & Molecular Biology

SOD mimics: From the tool box of the chemists to cellular studies

Clotilde Policar et al.

Summary: Superoxide dismutases (SODs) are metalloproteins that protect cells from oxidative stress by controlling the concentration of superoxide. Recent studies have shown that some SOD mimics designed to react with superoxide could indirectly enhance cellular antioxidant defenses. Understanding the bioactivity of these SOD mimics requires information on their cell-penetration, speciation, and subcellular location.

CURRENT OPINION IN CHEMICAL BIOLOGY (2022)

Review Food Science & Technology

The enzyme-modified comet assay: Past, present and future

Damian Muruzabal et al.

Summary: The enzyme-modified comet assay has been developed to detect various types of DNA lesions beyond the standard version, and has applications in human biomonitoring, environmental toxicology, genotoxicity testing, and basic research. Twelve enzymes have been employed, with some being extensively used while others less so. Additional enzymes could potentially expand the range of detectable DNA lesions and play a crucial role in understanding the mechanism of genotoxins.

FOOD AND CHEMICAL TOXICOLOGY (2021)

Review Cell Biology

Ferroptosis: mechanisms, biology and role in disease

Xuejun Jiang et al.

Summary: Ferroptosis, as a form of regulated cell death driven by iron-dependent phospholipid peroxidation, has seen significant growth in research in recent years. Studies have focused on molecular mechanisms, regulation, and functions of ferroptosis, linking this cell death modality to various pathologies and proposing its roles in normal physiology and potential therapeutic targeting.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2021)

Review Pharmacology & Pharmacy

The mechanism of action of N-acetylcysteine (NAC): The emerging role of H2S and sulfane sulfur species

Brandan Pedre et al.

Summary: Originally used as a mucolytic, N-acetylcysteine (NAC) is now a standard treatment for paracetamol poisoning and a widely used antioxidant. In addition to its traditional mechanisms, a newly discovered mechanism involves the conversion of NAC into hydrogen sulfide and sulfane sulfur species, which may explain many of its effects.

PHARMACOLOGY & THERAPEUTICS (2021)

Article Multidisciplinary Sciences

Evaluation of borinic acids as new, fast hydrogen peroxide-responsive triggers

Blaise Gatin-Fraudet et al.

Summary: A novel borinic-based fluorescent probe has been developed to address the slow kinetics issue of existing designs in rapid activation by H2O2. The probe showed a reaction rate towards H2O2 10,000 times faster than its boronic counterpart, making it effective in releasing effectors like fluorescent moieties in a cellular context.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2021)

Article Multidisciplinary Sciences

The mitochondrial thioredoxin reductase system (TrxR2) in vascular endothelium controls peroxynitrite levels and tissue integrity

Petra Kameritsch et al.

Summary: The study reveals the crucial role of endothelial TrxR2 in regulating the steady-state concentration of peroxynitrite and maintaining vascular integrity. Deletion of the TrxR2 gene leads to increased vascular stiffness, hypertrophy, and renal abnormalities. Loss of TrxR2 results in elevated peroxynitrite levels in both vascular endothelial cells and vessels, indicating a potential disruption of vascular homeostasis.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2021)

Review Nutrition & Dietetics

Vitamin A and Vitamin E: Will the Real Antioxidant Please Stand Up?

William S. Blaner et al.

Summary: This review focuses on the mechanisms of action of vitamin A and vitamin E in the body, suggesting that vitamin A acts as an indirect antioxidant by transcriptionally regulating genes involved in antioxidant responses, while vitamin E functions as a direct antioxidant and helps prevent the increase of peroxidized lipids that affect metabolic pathways and gene expression profiles. The review also discusses the lack of compelling evidence for a direct transcriptional mechanism of vitamin E similar to that of vitamin A.

ANNUAL REVIEW OF NUTRITION, VOL 41, 2021 (2021)

Letter Biophysics

Carbon dioxide redox metabolites in oxidative eustress and oxidative distress

Ohara Augusto et al.

Summary: High carbon dioxide tensions are toxic to mammals through both pH-dependent and pH-independent mechanisms, involving reactions with oxygen metabolites to produce redox-active metabolites. The potential role of these carbon dioxide redox metabolites in oxidative eustress and oxidative distress conditions warrants further discussion.

BIOPHYSICAL REVIEWS (2021)

Article Biochemistry & Molecular Biology

Quantification of 8-oxo-7,8-dihydro-2′-deoxyguanosine and 8-oxo-7,8-di-hydro-guanosine concentrations in urine and plasma for estimating 24-h urinary output

Trine Henriksen et al.

Summary: The analysis methods for 8-oxodGuo and 8-oxoGuo in plasma have not been established, and the existing plasma values in literature vary greatly. A new liquid chromatography mass spectrometry method allows estimation of 8-oxoGuo production from a single plasma sample, but the measurement methods for 8-oxodGuo remains controversial.

FREE RADICAL BIOLOGY AND MEDICINE (2021)

Review Biochemistry & Molecular Biology

Redox metabolism: ROS as specific molecular regulators of cell signaling and function

Claudia Lennicke et al.

Summary: Redox reactions play a crucial role in energy metabolism and physiological functions of organisms. Reactive oxygen species (ROS), such as hydrogen peroxide, are important derivatives in normal aerobic metabolism. Hydrogen peroxide can modify protein activity by oxidizing cysteine residues, affecting enzyme and transcription factor functions and cellular processes.

MOLECULAR CELL (2021)

Review Biotechnology & Applied Microbiology

Targeting oxidative stress in disease: promise and limitations of antioxidant therapy

Henry Jay Forman et al.

Summary: Oxidative stress plays a role in various diseases, and understanding the mechanisms behind antioxidants and how to enhance antioxidant defences may lead to greater pharmacological success.

NATURE REVIEWS DRUG DISCOVERY (2021)

Article Medicine, Research & Experimental

An in silico kinetic model of 8-oxo-7,8-dihydro-2-deoxyguanosine and 8-oxo-7,8-dihydroguanosine metabolism from intracellular formation to urinary excretion

Anders Jorgensen et al.

Summary: The excretion of 8-oxodG in urine is closely correlated to rates of damage and intracellular 8-oxodG levels, but independent of the rate of cellular removal. Steady state was calculated to occur within approximately 12 hours.

SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION (2021)

Article Cell Biology

Reactive Oxygen Species: Not Omnipresent but Important in Many Locations

Marc Herb et al.

Summary: Reactive oxygen species (ROS) play important roles in cellular processes but can also lead to diseases, their effects depending on cell type and ROS production conditions. Cellular redox balance, like cell pH and calcium levels, is tightly controlled, with evidence showing that cells regulate ROS production by controlling activation and localization factors.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)

Review Chemistry, Multidisciplinary

Activity-Based Sensing for Site-Specific Proteomic Analysis of Cysteine Oxidation

Yunlong Shi et al.

ACCOUNTS OF CHEMICAL RESEARCH (2020)

Article Biochemistry & Molecular Biology

A Quantitative Tissue-Specific Landscape of Protein Redox Regulation during Aging

Haopeng Xiao et al.

Review Biochemistry & Molecular Biology

Introduction to approaches and tools for the evaluation of protein cysteine oxidation

Leslie B. Poole et al.

PROTEIN OXIDATION (2020)

Review Spectroscopy

Recent development of synthetic probes for detection of hypochlorous acid/hypochlorite

Chenggong Ma et al.

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY (2020)

Article Biochemistry & Molecular Biology

Absolute quantitative analysis of intact and oxidized amino acids by LC-MS without prior derivatization

Luke F. Gamon et al.

REDOX BIOLOGY (2020)

Review Biochemistry & Molecular Biology

Moving forward with isoprostanes, neuroprostanes and phytoprostanes: where are we now?

Omar S. Ahmed et al.

LIPID MEDIATORS (2020)

Review Biochemistry & Molecular Biology

Reflections of an aging free radical

Barry Halliwell

FREE RADICAL BIOLOGY AND MEDICINE (2020)

Article Biochemistry & Molecular Biology

Methionine in Proteins: It's Not Just for Protein Initiation Anymore

Jung Mi Lim et al.

NEUROCHEMICAL RESEARCH (2019)

Review Biochemistry & Molecular Biology

Redox proteomics and amyloid β-peptide: insights into Alzheimer disease

D. Allan Butterfield et al.

JOURNAL OF NEUROCHEMISTRY (2019)

Article Biochemistry & Molecular Biology

Strategies to detect mitochondrial oxidants

Alicia J. Kowaltowski

REDOX BIOLOGY (2019)

Review Biochemistry & Molecular Biology

Carbon dioxide-catalyzed peroxynitrite reactivity - The resilience of the radical mechanism after two decades of research

Ohara Augusto et al.

FREE RADICAL BIOLOGY AND MEDICINE (2019)

Review Biochemistry & Molecular Biology

Recent development on liquid chromatography-mass spectrometry analysis of oxidized lipids

Luxiao Li et al.

FREE RADICAL BIOLOGY AND MEDICINE (2019)

Article Biochemistry & Molecular Biology

Mitochondrial morphology regulates organellar Ca2+ uptake and changes cellular Ca2+ homeostasis

Alicia J. Kowaltowski et al.

FASEB JOURNAL (2019)

Article Biochemistry & Molecular Biology

Analysis of protein chlorination by mass spectrometry

Tina Nybo et al.

REDOX BIOLOGY (2019)

Review Biochemistry & Molecular Biology

Detection and quantification of nitric oxide- derived oxidants in biological systems

Matias N. Moeller et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2019)

Review Biochemistry & Molecular Biology

Detection, identification, and quantification of oxidative protein modifications

Clare L. Hawkins et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2019)

Review Biochemistry & Molecular Biology

Interventions targeted at oxidatively generated modifications of nucleic acids focused on urine and plasma markers

Emil List Larsen et al.

FREE RADICAL BIOLOGY AND MEDICINE (2019)

Review Biochemistry & Molecular Biology

Biological Production, Detection, and Fate of Hydrogen Peroxide

Christine C. Winterbourn

ANTIOXIDANTS & REDOX SIGNALING (2018)

Review Biochemistry & Molecular Biology

In Vivo Imaging of Hydrogen Peroxide with HyPer Probes

Dmitry S. Bilan et al.

ANTIOXIDANTS & REDOX SIGNALING (2018)

Review Chemistry, Multidisciplinary

Biochemistry of Peroxynitrite and Protein Tyrosine Nitration

Gerardo Ferrer-Sueta et al.

CHEMICAL REVIEWS (2018)

Editorial Material Cardiac & Cardiovascular Systems

Redox Regulation Beyond ROS: Why ROS Should Not Be Measured as Often

Ralf P. Brandes et al.

CIRCULATION RESEARCH (2018)

Article Multidisciplinary Sciences

Chemogenetic generation of hydrogen peroxide in the heart induces severe cardiac dysfunction

Benjamin Steinhorn et al.

NATURE COMMUNICATIONS (2018)

Article Biochemical Research Methods

A biotin enrichment strategy identifies novel carbonylated amino acids in proteins from human plasma

Jesper F. Havelund et al.

JOURNAL OF PROTEOMICS (2017)

Article Multidisciplinary Sciences

Redox-based reagents for chemoselective methionine bioconjugation

Shixian Lin et al.

SCIENCE (2017)

Article Biochemistry & Molecular Biology

MitoNeoD: A Mitochondria-Targeted Superoxide Probe

Maria M. Shchepinova et al.

CELL CHEMICAL BIOLOGY (2017)

Review Biochemical Research Methods

The Expanding Landscape of the Thiol Redox Proteome

Jing Yang et al.

MOLECULAR & CELLULAR PROTEOMICS (2016)

Article Biochemistry & Molecular Biology

Real-time monitoring of basal H2O2 levels with peroxiredoxin-based probes

Bruce Morgan et al.

NATURE CHEMICAL BIOLOGY (2016)

Review Biochemistry & Molecular Biology

Chemical Approaches to Discovery and Study of Sources and Targets of Hydrogen Peroxide Redox Signaling Through NADVII Oxidase Proteins

Thomas F. Brewer et al.

ANNUAL REVIEW OF BIOCHEMISTRY, VOL 84 (2015)

Review Biochemistry & Molecular Biology

Clinical Relevance of Biomarkers of Oxidative Stress

Jeroen Frijhoff et al.

ANTIOXIDANTS & REDOX SIGNALING (2015)

Article Biochemistry & Molecular Biology

Even free radicals should follow some rules: A Guide to free radical research terminology and methodology

Henry Jay Forman et al.

FREE RADICAL BIOLOGY AND MEDICINE (2015)

Review Biochemistry & Molecular Biology

Detection of superoxide anion and hydrogen peroxide production by cellular NADPH oxidases

William M. Nauseef

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2014)

Review Biochemistry & Molecular Biology

The challenges of using fluorescent probes to detect and quantify specific reactive oxygen species in living cells

Christine C. Winterbourn

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2014)

Article Biochemistry & Molecular Biology

Multiparametric optical analysis of mitochondrial redox signals during neuronal physiology and pathology in vivo

Michael Breckwoldt et al.

NATURE MEDICINE (2014)

Article Chemistry, Medicinal

Boronate Probes as Diagnostic Tools for Real Time Monitoring of Peroxynitrite and Hydroperoxides

Jacek Zielonka et al.

CHEMICAL RESEARCH IN TOXICOLOGY (2012)

Editorial Material Biochemistry & Molecular Biology

Measuring reactive oxygen and nitrogen species with fluorescent probes: challenges and limitations

Balaraman Kalyanaraman et al.

FREE RADICAL BIOLOGY AND MEDICINE (2012)

Review Biochemistry & Molecular Biology

RNA modifications by oxidation: A novel disease mechanism?

Henrik E. Poulsen et al.

FREE RADICAL BIOLOGY AND MEDICINE (2012)

Article Biochemistry & Molecular Biology

Global Profiling of Reactive Oxygen and Nitrogen Species in Biological Systems HIGH-THROUGHPUT REAL-TIME ANALYSES

Jacek Zielonka et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2012)

Review Chemistry, Multidisciplinary

Boronate Oxidation as a Bioorthogonal Reaction Approach for Studying the Chemistry of Hydrogen Peroxide in Living Systems

Alexander R. Lippert et al.

ACCOUNTS OF CHEMICAL RESEARCH (2011)

Article Cell Biology

Unraveling the Biological Roles of Reactive Oxygen Species

Michael P. Murphy et al.

CELL METABOLISM (2011)

Review Chemistry, Multidisciplinary

Free Radical Lipid Peroxidation: Mechanisms and Analysis

Huiyong Yin et al.

CHEMICAL REVIEWS (2011)

Article Chemistry, Medicinal

Ex Vivo Oxidation in Tissue and Plasma Assays of Hydroxyoctadecadienoates: Z,E/E,E Stereoisomer Ratios

Wei Liu et al.

CHEMICAL RESEARCH IN TOXICOLOGY (2010)

Article Multidisciplinary Sciences

Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1

Jaime N. Guzman et al.

NATURE (2010)

Article Multidisciplinary Sciences

In vivo imaging of hydrogen peroxide production in a murine tumor model with a chemoselective bioluminescent reporter

Genevieve C. Van de Bittner et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Review Biochemistry & Molecular Biology

Lipid peroxidation: Physiological levels and dual biological effects

Etsuo Niki

FREE RADICAL BIOLOGY AND MEDICINE (2009)

Review Biochemistry & Molecular Biology

Quantification of protein modification by oxidants

Clare L. Hawkins et al.

FREE RADICAL BIOLOGY AND MEDICINE (2009)

Review Biochemistry & Molecular Biology

Redox-based regulation of signal transduction: Principles, pitfalls, and promises

Yvonne M. W. Janssen-Heininger et al.

FREE RADICAL BIOLOGY AND MEDICINE (2008)

Article Biochemistry & Molecular Biology

Molecular imaging of hydrogen peroxide produced for cell signaling

Evan W. Miller et al.

NATURE CHEMICAL BIOLOGY (2007)

Article Biochemistry & Molecular Biology

Mass spectrometric analysis demonstrates that BODIPY 581/591 C11 overestimates and inhibits oxidative lipid damage

Matthew L. MacDonald et al.

FREE RADICAL BIOLOGY AND MEDICINE (2007)

Article Cell Biology

Detection of protein carbonyls in aging liver tissue: A fluorescence-based proteornic approach

Asish R. Chaudhuri et al.

MECHANISMS OF AGEING AND DEVELOPMENT (2006)

Article Biochemical Research Methods

Susceptibility of actin to modification by 4-hydroxy-2-nonenal

M Ozeki et al.

JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES (2005)

Article Biotechnology & Applied Microbiology

F2-isoprostanes as markers of oxidative stress in vivo:: An overview

GL Milne et al.

BIOMARKERS (2005)