Multifunctional 3D sponge-like macroporous cryogel-modified long carbon fiber reinforced polyetheretherketone implants with enhanced vascularization and osseointegration

Article Engineering, Multidisciplinary

3D-printed porous PEEK scaffold combined with CSMA/POSS bioactive surface: A strategy for enhancing osseointegration of PEEK implants

Zhewen Liu et al.

Summary: By integrating the modified CSMA/POSS bioactive microporous surface with PEEK scaffolds, enhanced protein adsorption and bone formation can be achieved, showing promising potential for improving osseointegration.

COMPOSITES PART B-ENGINEERING (2022)

添加到收藏夹

Article Engineering, Multidisciplinary

Additively-manufactured PEEK/HA porous scaffolds with excellent osteogenesis for bone tissue repairing

Jibao Zheng et al.

Summary: PEEK/HA scaffolds improved osseointegration with host bone and enhanced the activity of BMSCs. Micro-CT and histological staining results showed higher bone ingrowth volume and better osteointegration effect of PEEK/HA scaffolds in comparison to pure PEEK scaffolds.

COMPOSITES PART B-ENGINEERING (2022)

添加到收藏夹

Article Materials Science, Biomaterials

Icariin-loaded sulfonated polyetheretherketone with osteogenesis promotion and osteoclastogenesis inhibition properties via immunomodulation for advanced osseointegration

Haobu Chai et al.

Summary: Loading icariin onto 3D porous sulfonated PEEK (SPEEK) enhanced osseointegration, promoted macrophage polarization and osteogenesis, inhibited osteoclastogenesis, regulated immune response, and improved the performance of orthopedic biomaterials.

JOURNAL OF MATERIALS CHEMISTRY B (2022)

添加到收藏夹

Review Cell & Tissue Engineering

Recent advances in smart stimuli-responsive biomaterials for bone therapeutics and regeneration

Hongpu Wei et al.

Summary: Bone defects combined with tumors, infections, or other bone diseases are challenging in clinical practice. To address this problem, researchers have designed various implantable biomaterials that can play a role in bone therapy and regeneration. External physical stimuli, endogenous disease microenvironments, and multiple integrated strategies can improve bone tissue therapy and regeneration.

BONE RESEARCH (2022)

添加到收藏夹

Article Engineering, Environmental

A 3D chemotactic-thermo-promo bacterial hunting system: Programmatic bacterial attract, capture, killing and healing the wound

Ling Xiao et al.

Summary: A smart nanohybrid has been developed to hunt and kill multidrug-resistant Pseudomonas aeruginosa using photothermal therapy, with additional anti-inflammatory and pro-cell proliferation effects during wound healing. This antibiotic-free nanohybrid shows promise in avoiding tissue damage and eliminating bacteria without leaving drug residue in the tissue.

CHEMICAL ENGINEERING JOURNAL (2021)

添加到收藏夹

Article Engineering, Biomedical

Induction of M2-Type Macrophage Differentiation for Bone Defect Repair via an Interpenetration Network Hydrogel with a GO-Based Controlled Release System

Min Zou et al.

Summary: The hydrogel loaded with IL-4 and BMP-2 shows promising effects in reducing inflammation, promoting macrophage M2-type differentiation, and enhancing bone regeneration after implantation, offering a potential strategy for future bone tissue engineering applications.

ADVANCED HEALTHCARE MATERIALS (2021)

添加到收藏夹

Article Materials Science, Composites

The influence of long carbon fiber and its orientation on the properties of three-dimensional needle-punched CF/PEEK composites

Wenyan Zhao et al.

Summary: The study aimed to obtain high performance composite materials with high mechanical strength and isotropic properties through optimizing the preparation parameters. Increasing carbon fiber content resulted in improved mechanical and thermal properties of the composites, showing multi-direction impregnation channels advantage.

COMPOSITES SCIENCE AND TECHNOLOGY (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Injectable GelMA Cryogel Microspheres for Modularized Cell Delivery and Potential Vascularized Bone Regeneration

Zuoying Yuan et al.

Summary: The study focuses on preparing porous shape-memory cryogel microspheres (CMS) with a certain pore size from methacrylated gelatin (GelMA), which effectively delivers multiple cells and enhances cell viability. Results indicate the potential of this technique in promoting tissue regeneration, especially in bone tissue engineering.

SMALL (2021)

添加到收藏夹

Article Engineering, Biomedical

Biomimetic Ti-6Al-4V alloy/gelatin methacrylate hybrid scaffold with enhanced osteogenic and angiogenic capabilities for large bone defect restoration

Limin Ma et al.

Summary: Titanium-based scaffolds are commonly used for bone defect treatment, but conventional implants lack adequate biomechanical properties for bone integration. A novel Ti-6Al-4V alloy/GelMA hybrid scaffold (GMPT) was developed with dual bionic features for bone defect repair, showing improved osteogenic and angiogenic capabilities. The concentration of GelMA significantly influenced gene expression related to bone formation and angiogenesis pathways in the GMPT scaffold, demonstrating promise for large bone defect restoration.

BIOACTIVE MATERIALS (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Nutrient Element Decorated Polyetheretherketone Implants Steer Mitochondrial Dynamics for Boosted Diabetic Osseointegration

Hao Wang et al.

Summary: This study introduced a novel mitochondria-targeted orthopedic implant with Zn2+ and Sr2+ modulation capability for enhancing bone formation and osseointegration in diabetic patients. The implant demonstrated the ability to recuperate mitochondrial dynamic disequilibrium and dysfunction in hyperglycemic conditions, ultimately enhancing osteogenicity of osteoblasts. In vivo evaluations further confirmed that nutrient element coatings substantially augment bone remodeling and osseointegration.

ADVANCED SCIENCE (2021)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Effect of Pore Size on Cell Behavior Using Melt Electrowritten Scaffolds

Yu Han et al.

Summary: The study revealed that scaffold pore size has significant effects on cell adhesion, proliferation, and differentiation. Different cell types demonstrated varying preferences for scaffold pore sizes, leading to differences in cell viability. The architecture of scaffolds should be tailored based on cell type and pore size for optimal tissue engineering strategies.

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2021)

添加到收藏夹

Article Nanoscience & Nanotechnology

Vacancy-Enhanced Photothermal Killing of Bacteria Mediated by Graphene Oxide

Xue Chen et al.

Summary: Two graphene oxide (GO) samples, GO-V11 and GO-V9, were prepared and compared for their photothermal antibacterial properties. GO-V9 showed higher efficiency than GO-V11 due to its higher photothermal conversion efficiency. The difference in their energy band structures impacted their photothermal antibacterial performance.

ACS APPLIED BIO MATERIALS (2021)

添加到收藏夹

Article Engineering, Biomedical

Three-dimensional cryogel matrix for spheroid formation and anti-cancer drug screening

Archana Singh et al.

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A (2020)

添加到收藏夹

Article Engineering, Biomedical

Periosteal matrix-derived hydrogel promotes bone repair through an early immune regulation coupled with enhanced angio- and osteogenesis

Pengcheng Qiu et al.

BIOMATERIALS (2020)

添加到收藏夹

Article Nanoscience & Nanotechnology

Multifunctional Surface with Enhanced Angiogenesis for Improving Long-Term Osteogenic Fixation of Poly(ether ether ketone) Implants

Taosheng Dong et al.

ACS APPLIED MATERIALS & INTERFACES (2020)

添加到收藏夹

Article Materials Science, Biomaterials

Delivery of Salvianolic Acid B for Efficient Osteogenesis and Angiogenesis from Silk Fibroin Combined with Graphene Oxide

Wei Wang et al.

ACS BIOMATERIALS SCIENCE & ENGINEERING (2020)

添加到收藏夹

Article Engineering, Biomedical

Sequential growth factor releasing double cryogel system for enhanced bone regeneration

Seunghun S. Lee et al.

BIOMATERIALS (2020)

添加到收藏夹

Article Engineering, Biomedical

Gaseous sulfur trioxide induced controllable sulfonation promoting biomineralization and osseointegration of polyetheretherketone implants

Teng Wan et al.

BIOACTIVE MATERIALS (2020)

添加到收藏夹

Article Engineering, Biomedical

Development of a New Bone-Mimetic Surface Treatment Platform: Nanoneedle Hydroxyapatite (nnHA) Coating

Kian F. Eichholz et al.

ADVANCED HEALTHCARE MATERIALS (2020)

添加到收藏夹

Article Engineering, Biomedical

In situ syntheses of hydroxyapatite-grafted graphene oxide composites

Ilaria Iacoboni et al.

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A (2019)

添加到收藏夹

Article Materials Science, Biomaterials

Rational design of gelatin/nanohydroxyapatite cryogel scaffolds for bone regeneration by introducing chemical and physical cues to enhance osteogenesis of bone marrow mesenchymal stem cells

K. T. Shalumon et al.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2019)

添加到收藏夹

Article Chemistry, Applied

In-situ bonding technology and excellent anticorrosion activity of graphene oxide / hydroxyapatite nanocomposite pigment

Xi-Zi Xue et al.

DYES AND PIGMENTS (2019)

添加到收藏夹

Article Nanoscience & Nanotechnology

Mussel-Inspired Polydopamine Coating: A General Strategy To Enhance Osteogenic Differentiation and Osseointegration for Diverse Implants

Hui Wang et al.

ACS APPLIED MATERIALS & INTERFACES (2019)

添加到收藏夹

Article Nanoscience & Nanotechnology

Enhanced Osteogenic Differentiation of Stem Cells on Phase-Engineered Graphene Oxide

Jia-Wei Yang et al.

ACS APPLIED MATERIALS & INTERFACES (2018)

添加到收藏夹

Article Biochemistry & Molecular Biology

Heparin Functionalized Injectable Cryogel with Rapid Shape-Recovery Property for Neovascularization

Inseon Kim et al.

BIOMACROMOLECULES (2018)

添加到收藏夹

Article Biophysics

Micro-porous polyetheretherketone implants decorated with BMP-2 via phosphorylated gelatin coating for enhancing cell adhesion and osteogenic differentiation

Jiuping Wu et al.

COLLOIDS AND SURFACES B-BIOINTERFACES (2018)

添加到收藏夹

Article Biochemistry & Molecular Biology

Graphene-Oxide-Decorated Microporous Polyetheretherketone with Superior Antibacterial Capability and In Vitro Osteogenesis for Orthopedic Implant

Ling Ouyang et al.

MACROMOLECULAR BIOSCIENCE (2018)

添加到收藏夹

Article Materials Science, Biomaterials

One-step fabrication of functionalized poly(etheretherketone) surfaces with enhanced biocompatibility and osteogenic activity

Sidi Liu et al.

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2018)

添加到收藏夹

Article Chemistry, Multidisciplinary

3D Fabrication with Integration Molding of a Graphene Oxide/Polycaprolactone Nanoscaffold for Neurite Regeneration and Angiogenesis

Yun Qian et al.

ADVANCED SCIENCE (2018)

添加到收藏夹

Article Materials Science, Multidisciplinary

Osteogenesis and Antibacterial Activity of Graphene Oxide and Dexamethasone Coatings on Porous Polyetheretherketone via Polydopamine-Assisted Chemistry

Ling Ouyang et al.

COATINGS (2018)

添加到收藏夹

Article Nanoscience & Nanotechnology

Immunomodulatory properties of graphene oxide for osteogenesis and angiogenesis

Deting Xue et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2018)

添加到收藏夹

Article Polymer Science

Bioglass-Incorporated Methacrylated Gelatin Cryogel for Regeneration of Bone Defects

Song Kwon et al.

POLYMERS (2018)

添加到收藏夹

Review Polymer Science

Cryostructuring of Polymeric Systems. 50. Cryogels and Cryotropic Gel-Formation: Terms and Definitions

Vladimir I. Lozinsky

GELS (2018)

添加到收藏夹

Article Materials Science, Biomaterials

Improved biotribological properties of PEEK by photo-induced graft polymerization of acrylic acid

Xiaoduo Zhao et al.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2017)

添加到收藏夹

Article Materials Science, Biomaterials

Biohybrid methacrylated gelatin/polyacrylamide hydrogels for cartilage repair

Lu Han et al.

JOURNAL OF MATERIALS CHEMISTRY B (2017)

添加到收藏夹

Review Engineering, Biomedical

A comprehensive review of cryogels and their roles in tissue engineering applications

Katherine R. Hixon et al.

ACTA BIOMATERIALIA (2017)

添加到收藏夹

Article Nanoscience & Nanotechnology

One-Dimensional Hydroxyapatite Nanostructures with Tunable Length for Efficient Stem Cell Differentiation Regulation

Baojin Ma et al.

ACS APPLIED MATERIALS & INTERFACES (2017)

添加到收藏夹

Article Cell Biology

Cellular behaviours of bone marrow-derived mesenchymal stem cells towards pristine graphene oxide nanosheets

Changbo Wei et al.

CELL PROLIFERATION (2017)

添加到收藏夹

Article Biophysics

Electrochemical synthesis of three-dimensional porous reduced graphene oxide film: Preparation and in vitro osteogenic activity evaluation

Zizhu Tian et al.

COLLOIDS AND SURFACES B-BIOINTERFACES (2017)

添加到收藏夹

Article Engineering, Biomedical

Immunomodulatory and angiogenic responses induced by graphene oxide scaffolds in chronic spinal hemisected rats

Elisa Lopez-Dolado et al.

BIOMATERIALS (2016)

添加到收藏夹

Article Engineering, Biomedical

Graphene Oxides Show Angiogenic Properties

Sudip Mukherjee et al.

ADVANCED HEALTHCARE MATERIALS (2015)

添加到收藏夹

Article Chemistry, Physical

Mechanical properties and biomedical applications of a nanotube hydroxyapatite-reduced graphene oxide composite

S. Baradaran et al.

CARBON (2014)

添加到收藏夹

Review Chemistry, Medicinal

Nanotoxicity of Graphene and Graphene Oxide

Amedea B. Seabra et al.

CHEMICAL RESEARCH IN TOXICOLOGY (2014)

添加到收藏夹

Article Chemistry, Applied

UV-light assisted single step route to functional PEEK surfaces

Ahmed Yousaf et al.

REACTIVE & FUNCTIONAL POLYMERS (2014)

添加到收藏夹

Article Chemistry, Physical

Biomimetically-mineralized composite coatings on titanium functionalized with gelatin methacrylate hydrogels

Guoxin Tan et al.

APPLIED SURFACE SCIENCE (2013)

添加到收藏夹

Review Cell & Tissue Engineering

Three-Dimensional Scaffolds for Tissue Engineering Applications: Role of Porosity and Pore Size

Qiu Li Loh et al.

TISSUE ENGINEERING PART B-REVIEWS (2013)

添加到收藏夹

Article Chemistry, Multidisciplinary

Micro-/Nano-sized hydroxyapatite directs differentiation of rat bone marrow derived mesenchymal stem cells towards an osteoblast lineage

Yan Huang et al.

NANOSCALE (2012)

添加到收藏夹

Review Chemistry, Multidisciplinary

The chemistry of graphene oxide

Daniel R. Dreyer et al.

CHEMICAL SOCIETY REVIEWS (2010)

添加到收藏夹

Review Polymer Science

Developments and new applications of UV-induced surface graft polymerizations

Jianping Deng et al.

PROGRESS IN POLYMER SCIENCE (2009)

添加到收藏夹

Article Construction & Building Technology

Tensile bonding strength of epoxy coatings to concrete substrate

J Liu et al.

CEMENT AND CONCRETE RESEARCH (2005)

添加到收藏夹

Article Engineering, Biomedical

Preparation of hydroxyapatite-gelatin nanocomposite

MC Chang et al.

BIOMATERIALS (2003)

添加到收藏夹

Multifunctional 3D sponge-like macroporous cryogel-modified long carbon fiber reinforced polyetheretherketone implants with enhanced vascularization and osseointegration

相关参考文献

导出引文

分享论文