ISOLATION OF IKAHONONE, 4-METHYL-2,4-DIHYDROXY-3-PENTANONE FROM BACILLUS CEREUS IFM12235

A new ketone, ikahonone (1), and five known compounds (2-6) were isolated from Bacillus cereus IFM12235 collected in Japan. The structure of compound 1 was elucidated using spectral studies, including NMR. The absolute configurations of 1 and 2 were determined by comparing electronic circular dichroism (ECD) spectra with known compounds and calculating the ECD spectra of 1 and 2. Three compounds (2-4) were previously prepared by synthesis, and first isolated as natural products in the present study.

Automated summary

A new ketone, ikahonone (1), and five known compounds (2-6) were isolated from Bacillus cereus IFM12235 collected in Japan. The structure of compound 1 was elucidated using spectral studies, including NMR. The absolute configurations of 1 and 2 were determined by comparing ECD spectra with known compounds and calculating the ECD spectra of 1 and 2. Additionally, three compounds (2-4) were synthesized previously but first isolated as natural products in this study.