期刊
BRAIN AND LANGUAGE
卷 231, 期 -, 页码 -出版社
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.bl.2022.105149
关键词
Functional connectivity; Functional magnetic resonance imaging (fMRI); Graph theory; Spoken word processing; Word processing development
资金
- National Natural Science Founda-tion of China [31970977, 31571155]
- Beijing Brain Initiative of Beijing Municipal Science & Technology Commission [Z181100001518003]
- 973 Program [2014CB846103]
- Interdisciplinary Research Funds of Beijing Normal University [2015KJJCB28]
- Fundamental Research Funds for the Central Universities [R01 HD042049]
- National Institute of Child Health and Human Develop-ment
Our study compared functional connectivity in language processing between children and adults using brain network analysis. We found that adults showed stronger connectivity between bilateral inferior frontal gyri and left inferior parietal lobule in the rhyming task, and between middle frontal gyrus and angular gyrus, as well as within occipital areas in the meaning task. Children, on the other hand, showed stronger connectivity in Heschl's gyrus, superior temporal gyrus, and subcortical areas. These findings suggest that the development of spoken word processing is characterized by increased functional specialization, with phonological and semantic processing relying on dorsal and ventral pathways, respectively.
A dual-stream dissociation for separate phonological and semantic processing has been implicated in adults' language processing, but it is unclear how this dissociation emerges with development. By employing a graph-theory based brain network analysis, we compared functional interaction architecture during a rhyming and meaning judgment task of children (aged 8-12) with adults (aged 19-26). We found adults had stronger func-tional connectivity strength than children between bilateral inferior frontal gyri and left inferior parietal lobule in the rhyming task, between middle frontal gyrus and angular gyrus, and within occipital areas in the meaning task. Meanwhile, adults but not children manifested between-task differences in these properties. In contrast, children had stronger functional connectivity strength or nodal degree in Heschl's gyrus, superior temporal gyrus, and subcortical areas. Our findings indicated spoken word processing development is characterized by increased functional specialization, relying on the dorsal and ventral pathways for phonological and semantic processing respectively.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据