期刊
CHEMICAL SCIENCE
卷 13, 期 29, 页码 8590-8596出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/d2sc02685f
关键词
-
资金
- Swedish Research Council (VR)
- Knut and Alice Wallenberg Foundation [KAW 2016:0072, KAW 2018:0066]
- Stiftelsen Olle Engkvist Byggmastare
- Sichuan Science and Technology Program [2021YFH0161]
- National Natural Science Foundation of China [21811530004]
- Swedish Foundation for International Cooperation in Research and Higher Education [STINT CH2017-7226]
In this study, a catalytic method for the asymmetric synthesis of enantioenriched products bearing fluoromethylated stereocenters with excellent yields and enantioselectivities was reported.
Fluoromethyl groups possess specific steric and electronic properties and serve as a bioisostere of alcohol, thiol, nitro, and other functional groups, which are important in an assortment of molecular recognition processes. Herein we report a catalytic method for the asymmetric synthesis of a variety of enantioenriched products bearing fluoromethylated stereocenters with excellent yields and enantioselectivities. Various N,P-ligands were designed and applied in the hydrogenation of fluoromethylated olefins and vinyl fluorides.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据